PNP Products
(Nucleoside Phosphorylase (NP))
Categories
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008].
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Featured PNP Categories
PNP Antibodies
High quality antibodies with extensive validation data.
PNP ELISA Kits
Reliable ELISA kits for a wide range of species.
PNP Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PNP Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, FACS, IHC (p)
Validations
- (6)
Cat. No.
ABIN5647213
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (5)
Cat. No.
ABIN4886701
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN948191
Quantity
100 μg
Datasheet
Datasheet
Recommended PNP ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4884203
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6384863
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Quantitative
Validations
Cat. No.
ABIN1057931
Quantity
96 tests
Datasheet
Datasheet
Recommended PNP Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3133362
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419154
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419160
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PNP products
: "CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis." in: Journal of hepatology, Vol. 69, Issue 3, pp. 705-717, (2018) (PubMed).: "Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer." in: British journal of cancer, Vol. 106, Issue 2, pp. 405-13, (2012) (PubMed).
Synonyms and alternative names related to PNP
purine nucleoside phosphorylase (PNP), purine nucleoside phosphorylase (Pnp), purine-nucleoside phosphorylase (Pnp), AL024301, AU015798, NP, Np, Np-1, Np-2, Pnp1, PRO1837, PUNPProtein level used designations for PNP
- inosine phosphorylase
- inosine-guanosine phosphorylase
- purine-nucleoside:orthophosphate ribosyltransferase
- nucleoside phosphorylase
- purine nucleoside phosphorylase
- purine-nucleoside phosphorylase 1
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