anti-Cow (Bovine) Mediterranean Fever antibody for Western Blotting

Recommended Mediterranean Fever Antibody (supplied by: Log in to see )

Antigen
Mediterranean Fever (MEFV) Antibodies
  • pyrin
  • MEFV
  • FMF
  • MEF
  • TRIM20
  • rfp domain
  • MEFV, pyrin innate immunity regulator
  • Mediterranean fever
  • MEFV
  • Mefv
Epitope
N-Term
19
18
9
5
5
5
5
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
65
3
2
2
2
1
1
1
1
1
1
Host
Rabbit
43
17
5
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
3
3
3
Application
Western Blotting (WB)
57
42
5
4
4
2
1
1
Options
Supplier
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Available images

Catalog No. ABIN2779421
$ 249.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
4 ABIN202912 WB Rabbit IgG N-Term Log in to see Polyclonal 0

General

Antigen Mediterranean Fever (MEFV) Antibodies
Epitope N-Term
(19), (18), (9), (5), (5), (5), (5), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
(65), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(43), (17), (5)
Clonality
Polyclonal
Conjugate Un-conjugated
(3), (3), (3), (3), (3), (3)
Application Western Blotting (WB)
(57), (42), (5), (4), (4), (2), (1), (1)
Pubmed 1 reference available
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Product details

Target Details Application Details Handling References Images
Sequence TPSDHLLSTL EELVPYDFEK FKFKLQNTSV QKEHSRIPRS QIQRARPVKM
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against MEFV. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human MEFV

Target Details

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Antigen
Alternative Name MEFV (MEFV Antibody Abstract)
Background MEFV was identified as the gene that when mutated causes Mediterranean fever, a hereditary periodic fever syndrome. MEFV is expressed in granulocytes and myeloid bone marrow precursors.
Alias Symbols: FMF, MEF, TRIM20
Protein Interaction Partner: COG5, PYCARD, PSTPIP1,
Protein Size: 781
Molecular Weight 86 kDa
Gene ID 4210
NCBI Accession NM_000243, NP_000234
UniProt O15553
Pathways Positive Regulation of Endopeptidase Activity

Application Details

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Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 781 AA

Restrictions For Research Use only

Handling

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Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

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Background publications

Giaglis, Mimidis, Papadopoulos, Thomopoulos, Sidiropoulos, Rafail, Nikolopoulou, Fragouli, Kartalis, Tzioufas, Boumpas, Ritis: "Increased frequency of mutations in the gene responsible for familial Mediterranean fever (MEFV) in a cohort of patients with ulcerative colitis: evidence for a potential disease-modifying effect?" in: Digestive diseases and sciences, Vol. 51, Issue 4, pp. 687-92, 2006

Images

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Supplier Images
Western Blotting (WB) image for anti-Mediterranean Fever (MEFV) (N-Term) antibody (ABIN2779421) WB Suggested Anti-MEFV Antibody Titration: 0.625ug/ml ELISA Titer: 1:62500 Positi...