anti-Human Mediterranean Fever antibody for Immunoprecipitation

Recommended Mediterranean Fever Antibody (supplied by: Log in to see )

Antigen
Mediterranean Fever (MEFV) Antibodies
  • pyrin
  • MEFV
  • FMF
  • MEF
  • TRIM20
  • rfp domain
  • MEFV, pyrin innate immunity regulator
  • Mediterranean fever
  • MEFV
  • Mefv
Epitope
AA 2-29
19
18
9
6
5
5
4
1
1
Reactivity
Human
65
4
3
3
3
2
2
2
1
1
1
Host
Rabbit
43
17
5
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
3
3
3
Application
Immunoprecipitation (IP), Western Blotting (WB)
57
42
4
4
4
2
1
1
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Supplier
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Supplier Product No.
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Catalog No. ABIN1169260
$ 529.69
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2577853 IP WB Rabbit AA 2-29 Log in to see Polyclonal 0
1 ABIN5690335 IP WB Rabbit AA 2-29 Log in to see Polyclonal 0
1 ABIN2963952 IP WB Rabbit AA 2-29, N-Term Log in to see Polyclonal 0
1 ABIN2346423 IP WB Rabbit AA 2-29 Log in to see Polyclonal 0

General

Antigen Mediterranean Fever (MEFV) Antibodies
Epitope AA 2-29
(19), (18), (9), (6), (5), (5), (4), (1), (1)
Reactivity Human
(65), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1)
Host Rabbit
(43), (17), (5)
Clonality
Polyclonal
Conjugate Un-conjugated
(3), (3), (3), (3), (3), (3)
Application Immunoprecipitation (IP), Western Blotting (WB)
(57), (42), (4), (4), (4), (2), (1), (1)
Pubmed 1 reference available
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Product details

Target Details Application Details Handling References Images
Specificity Recognizes human pyrin.
Cross-Reactivity Human
Immunogen Synthetic peptide corresponding to aa 2-29 (A2KTPSDHLLSTLEELVPYDFEKFKFKLQ29) of human pyrin.

Target Details

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Antigen
Alternative Name Pyrin (MEFV Antibody Abstract)
Background Pyrin regulates inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed. Defects in pyrin are the cause for Mediterranean fever.
UniProt O15553
Pathways Positive Regulation of Endopeptidase Activity

Application Details

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Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 1 mg/mL
Buffer In PBS containing 10 % glycerol and 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date 12 months

References

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Product cited in:

Papin, Cuenin, Agostini, Martinon, Werner, Beer, Grütter, Grütter, Tschopp: "The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing." in: Cell death and differentiation, Vol. 14, Issue 8, pp. 1457-66, 2007