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anti-Human HLX Antibodies:
anti-Mouse (Murine) HLX Antibodies:
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Human Polyclonal HLX Primary Antibody for IF, WB - ABIN516528
Martin, Popov, Aguilo, OLoghlen, Raguz, Snijders, Dharmalingam, Li, Thymiakou, Carroll, Zeisig, So, Peters, Episkopou, Walsh, Gil: Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK?a regulation. in The EMBO journal 2013
HLX is a homeobox (show Lbx1 Antibodies) transcription factor gene which is relatively conserved across species. Hlx homozygous null mice have a short bowel and reduced muscle cells in the diaphragm, closely resembling the anomalies in the two fetuses and we therefore suggest that the HLX mutation in this family could explain the fetal findings
Two differentiation-related genes, HHEX (show HHEX Antibodies) and HLX, are promoters of early phase reprogramming toward pluripotency.
Prdm16 (show PRDM16 Antibodies) interacts with the transcription factor Hlx, which is stabilized in response to beta3-adrenergic signaling, to increase thermogenic gene expression and mitochondrial biogenesis in subcutaneous WAT.
HLX1 is significantly downregulated in HCC (show FAM126A Antibodies) and suggests that HLX1 has suppressive effects on HCC (show FAM126A Antibodies) growth and metastasis. Accordingly, HLX1 may act as a tumor suppressor in HCC (show FAM126A Antibodies).
Studies have identified HLX as a novel key transcription factor involved in the regulation of early hematopoiesis and AML (show RUNX1 Antibodies) pathogenesis.
The expression levels of Hlx, T-bet, and IFN-gamma (show IFNG Antibodies) were significantly decreased.
Data suggest that HLX1 is downstream mediator of hepatocyte growth factor- (HGF (show HGF Antibodies)-) induced cell survival, cell proliferation, and invasive properties of trophoblast cells; thus, both HGF (show HGF Antibodies) and HLX1 appear to be involved in normal placental development.
This study identifies HLX as a key regulator in immature hematopoietic and leukemia cells and as a prognostic marker and therapeutic target in acute myeloid leukemia (show BCL11A Antibodies).
This study investigated the influence of TBX21 and HLX1 single nucleotide polymorphisms (SNPs), which have previously been shown to be associated with asthma, on T(H)1/T(H)2 lineage cytokines at birth.
a functional polymorphism in HLX in combination with the TBX21 polymorphism is also associated with the prognosis of Graves' disease.
HLX is a homeobox (show PRRX1 Antibodies) transcription factor gene which is relatively conserved across species. Hlx homozygous null mice have a short bowel and reduced muscle cells in the diaphragm, closely resembling the anomalies in the two fetuses and we therefore suggest that the HLX mutation in this family could explain the fetal findings
methyl-CpG-binding domain protein 2 (MBD2 (show MBD2 Antibodies)), an epigenetic regulator, controls autoimmunity and EAE through T-bet/Hlx.
Hlx regulates sprouting in vitro, but its role in sprouting is nonessential in vivo. HLX is regulated by shear stress and a subtle defect in vascular remodeling is present in knockout embryos.
Results shown that over-expressed Hlx in DC2.4 up-regulated the transcription and expression of IFN-gamma, increased the expression of maturation makers including CD40, CD80, CD86, MHC-I and MHC-II
Transient over-expression of Hlx in DC2.4 promotes DC2.4 maturation and up-regulates IL-12 (show IL12A Antibodies), IL-10 (show IL10 Antibodies) and TGF-beta (show TGFB1 Antibodies) expression. H1x (show H1FX Antibodies) modified DC2.4 cells seem to function as regulatory dendritic cells
Hlx expression in activated NK cells temporally controls and limits the monokine-induced production of interferon-gamma (show IFNG Antibodies)
Hlx1 selectively marks sprouting endothelial cells during zebrafish development.Hlx1 is required for intersegmental vessel angiogenesis in zebrafish embryos.Hlx1 cell-autonomously maintains endothelial stalk cell potential.
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).
H2.0-like homeo box 1
, H2.0-like homeo box-1
, H2.0-like homeobox 1
, H2.0-like homeobox protein
, homeobox protein HB24
, homeobox protein HLX1
, H2.0-like homeobox
, LOW QUALITY PROTEIN: H2.0-like homeobox protein
, H2.0 homeobox 1