anti-Dog (Canine) Non-SMC Element 4 Homolog A (S. Cerevisiae) antibody for Immunofluorescence

Recommended Non-SMC Element 4 Homolog A (S. Cerevisiae) Antibody (supplied by: Log in to see )

Antigen
Non-SMC Element 4 Homolog A (S. Cerevisiae) (NSMCE4A) Antibodies
  • 2410003A14Rik
  • RGD1309025
  • C10orf86
  • NS4EA
  • NSE4A
  • NSE4 homolog A, SMC5-SMC6 complex component
  • Nsmce4a
  • NSMCE4A
Epitope
C-Term
11
11
8
2
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
28
Host
Rabbit
28
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunofluorescence (IF), Western Blotting (WB)
27
15
3
3
3
3
1
Options
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Available images

Catalog No. ABIN2791705
$ 319.00
Plus shipping costs $45.00

General

Antigen Non-SMC Element 4 Homolog A (S. Cerevisiae) (NSMCE4A) Antibodies
Epitope C-Term
(11), (11), (8), (2), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
(28)
Host Rabbit
(28)
Clonality
Polyclonal
Conjugate Un-conjugated
(2), (2), (2), (2), (2), (2)
Application Immunofluorescence (IF), Western Blotting (WB)
(27), (15), (3), (3), (3), (3), (1)
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Product details

Target Details Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN2183687
Sequence PVIQEERAMP AQLRRMEESH QEATEKEVER ILGLLQTYFR EDPDTPMSFF
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics This is a rabbit polyclonal antibody against NSMCE4A. It was validated on Western Blot.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C-terminal region of Human NSMCE4A

Target Details

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Antigen
Alternative Name NSMCE4A (NSMCE4A Antibody Abstract)
Background NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.
Alias Symbols: C10orf86, NS4EA, NSE4A
Protein Interaction Partner: UBC, HECW2, SRPK2, SRPK1, MAGED4B, NDNL2, MAGEC2, MAGEH1, MAGED2, NDN, MAGEB1, MAGEA1, NSMCE1, SMC6,
Protein Size: 385
Molecular Weight 44 kDa
Gene ID 54780
NCBI Accession NM_017615, NP_060085
UniProt Q9NXX6
Pathways Positive Regulation of Response to DNA Damage Stimulus

Application Details

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Restrictions For Research Use only

Handling

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Format Liquid
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

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Supplier Images
Western Blotting (WB) image for anti-Non-SMC Element 4 Homolog A (S. Cerevisiae) (NSMCE4A) (C-Term) antibody (ABIN2791705) Host: Rabbit Target Name: NSMCE4A Sample Type: Fetal Lung lysates Antibody Dilution: ...
Immunofluorescence (IF) image for anti-Non-SMC Element 4 Homolog A (S. Cerevisiae) (NSMCE4A) (C-Term) antibody (ABIN2791705) Sample Type : HCT116 Primary Antibody Dilution: 4 ug/ml Secondary Antibody : Anti-r...