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Human Monoclonal ICOSLG Primary Antibody for FACS - ABIN2689136
Bretscher: A two-step, two-signal model for the primary activation of precursor helper T cells. in Proceedings of the National Academy of Sciences of the United States of America 1999
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Human Monoclonal ICOSLG Primary Antibody for ELISA - ABIN610254
Mary, Charrasse, Meriane, Comunale, Travo, Blangy, Gauthier-Rouvière: Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism. in Molecular biology of the cell 2002
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Human Monoclonal ICOSLG Primary Antibody for CyTOF, FACS - ABIN4899396
Fos, Salles, Lang, Carrette, Audebert, Pastor, Ghiotto, Olive, Bismuth, Nunès: ICOS ligation recruits the p50alpha PI3K regulatory subunit to the immunological synapse. in Journal of immunology (Baltimore, Md. : 1950) 2008
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Human Polyclonal ICOSLG Primary Antibody for CyTOF, FACS - ABIN4899398
Jang, Park, Choi, Kim, Hwang, Baek, Suh, Mun, Suh: 12-O-tetradecanoyl phorbol 13-acetate induces the expression of B7-DC, -H1, -H2, and -H3 in K562 cells. in International journal of oncology 2007
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Human Monoclonal ICOSLG Primary Antibody for FACS - ABIN2479626
Youngnak-Piboonratanakit, Tsushima, Otsuki, Igarashi, Omura, Azuma: Expression and regulation of human CD275 on endothelial cells in healthy and inflamed mucosal tissues. in Scandinavian journal of immunology 2006
Human Monoclonal ICOSLG Primary Antibody for FACS - ABIN4896046
Schulte, Gielen, Kers-Rebel, Schreibelt, van Kuppeveld, Adema: Enterovirus-infected β-cells induce distinct response patterns in BDCA1+ and BDCA3+ human dendritic cells. in PLoS ONE 2015
Human Monoclonal ICOSLG Primary Antibody for FACS - ABIN4896047
Dianzani, Minelli, Gigliotti, Occhipinti, Giovarelli, Conti, Boggio, Shivakumar, Baldanzi, Malacarne, Orilieri, Cappellano, Fantozzi, Sblattero, Yagi, Rojo, Chiocchetti, Dianzani: B7h triggering inhibits the migration of tumor cell lines. in Journal of immunology (Baltimore, Md. : 1950) 2014
study confirms the importance of ICOSL shedding in ICOS (show ICOS Antibodies)/ICOSL function and expression and it identifies ADAM10 (show ADAM10 Antibodies) as the most important sheddase for controlling ICOSL levels
results showed that monocyte-derived osteoclast (OC)-like cells (MDOCs) express B7h during their differentiation, and that B7h triggering reversibly inhibits OC differentiation and function both in vitro and in vivo
study concludse that lymphopenia-driven autoimmunity and the development of Tfh17 cells in Rasgrp1 (show RASGRP1 Antibodies)-deficient mice occur independently of CD275(B7-H2)
The expression of ICOSL in the cornea and the ICOS (show ICOS Antibodies)-mediated induction of Foxp3 (show FOXP3 Antibodies)+ CD4 (show CD4 Antibodies)+ regulatory T cells may contribute to successful corneal allograft survival.
this study shows that sICOSL in the serum of healthy donors increases in an age-dependent manner and that the matrix metalloproteinase inhibitor (MMPI) could suppress sICOSL production
There was a clearly positive correlation between the presence of IL-17 (show IL17A Antibodies)-producing cells and ICOS (show ICOS Antibodies) expression in ICOSL KO mice; it also showed that Th17 was involved in the pathological tissue remodeling in liver fibrosis induced by schistosomiasis.
Selective ablation of ICOSL in CD11c (show ITGAX Antibodies)+ cells, but not in B cells, dramatically ameliorates kidney and lung inflammation in lupus-prone transgenic mice.
ICOS-ICOS (show ICOS Antibodies)-L interaction promoted cytokine production and survival in type 2 innate lymphoid cells through STAT5 (show STAT5A Antibodies) signaling in asthma.
restoring control of the T follicular helper-germinal center B-cell axis by blocking the ICOS (show ICOS Antibodies)-ICOSL pathway reduced the development of atherosclerosis and the formation of tertiary lymphoid organs.
ICOSL is a molecular linkage between T-B interactional dynamics and positive selection for high-affinity bone-marrow plasma cell formation; study reveals a pathway by which follicular T-helper cells control the quality of long-lived humoral immunity
this study found that B7-H2 expression on CD8 (show CD8A Antibodies)(+) T cells in colorectal cancer patients' tumor tissues was significantly higher than in non-tumor tissues
study confirms the importance of ICOSL shedding in ICOS (show CTLA4 Antibodies)/ICOSL function and expression and it identifies ADAM10 (show ADAM10 Antibodies) as the most important sheddase for controlling ICOSL levels
results showed that monocyte-derived osteoclast (OC)-like cells (MDOCs) express B7h (show CD274 Antibodies) during their differentiation, and that B7h (show CD274 Antibodies) triggering reversibly inhibits OC differentiation and function both in vitro and in vivo
The ICOS (show CTLA4 Antibodies) and ICOSL SNPs examined do not have an apparent effect on the disease susceptibility and prognosis of autoimmune thyroid diseases.
Loss-of-function mutations in NIK (show MAP3K14 Antibodies) cause impaired ICOSL expression.
ICOS-ICOS (show CTLA4 Antibodies)-L interaction promoted cytokine production and survival in type 2 innate lymphoid cells through STAT5 (show STAT5A Antibodies) signaling in asthma.
Our data show that mDCs from patients with AR display impaired expression of ICOSL, and this defect licenses mDCs to promote aberrant IL-13 (show IL13 Antibodies)- and IL-5 (show IL5 Antibodies)-producing Th2 cell responses.
These data suggest that rs2294020 SNP of FOXP3 (show FOXP3 Antibodies) gene and rs378299 SNP of ICOSLG gene are associated with alopecia areata and with a reduced expression of the FOXP3 (show FOXP3 Antibodies) and ICOSLG genes in alopecia patients.
a critical role is described for the rs7282490 ICOSLG region polymorphism associated with immune-mediated diseases in amplifying pattern-recognition receptor initiated inflammatory signaling and cytokine secretion
the B7h (show CD274 Antibodies)-ICOS (show CTLA4 Antibodies) interaction may modulate the spread of cancer metastases
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion\; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co- stimulating memory T-cell function (By similarity).
, ICOS ligand
, inducible T-cell co-stimulator ligand
, B7 homolog 2
, B7-like protein Gl50
, B7-related protein 1
, B7 homologue 2
, transmembrane protein B7-H2 ICOS ligand
, icos ligand