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|Antigen||Nucleoporin 153kDa (NUP153) Antibodies|
|Epitope||AA 610-1191 Alternatives|
|Reactivity||Rat (Rattus) Alternatives|
|Conjugate||This NUP153 antibody is un-conjugated Alternatives|
Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA, Western Blotting (WB)
|2 references available|
|Supplier||Log in to see|
Product Details anti-NUP153 AntibodyTarget Details NUP153 Application Details Handling References for anti-NUP153 antibody (ABIN2452062) Images
|Specificity||Specific to human, mouse, rat and monkey Nup153 proteins.|
|Cross-Reactivity (Details)||Not tested for other species|
|Characteristics||When injected into the nucleus,R4C8 accumulates into the nuclear pores of Hela cells. R4C8 works in immuno-cytochemistry very well.|
|Immunogen||Recombinant GST-fused rat Nup153 (610-1191aa, Zn finger and FG repeats domain)|
|Plasmids, Primers & others|
Target Details NUP153Product Details anti-NUP153 Antibody Application Details Handling References for anti-NUP153 antibody (ABIN2452062) Images back to top
|Alternative Name||Nup153 (NUP153 Antibody Abstract)|
|Background||The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nup (Nucleoporin) 153 is a large (153 kDa) O-linked glycoprotein which is a component of the basket structure located on the nucleoplasmic face of NPC. Nup153 plays a critical role in nuclear export of RNA and proteins. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by propriety chromatography processes.|
|Pathways||Protein targeting to Nucleus|
Application DetailsProduct Details anti-NUP153 Antibody Target Details NUP153 Handling References for anti-NUP153 antibody (ABIN2452062) Images back to top
1. Western blotting: 160 kDa single band in Hela cell extract
Other applications have not been tested.
When injected into the nucleus, R4C8 accumulates into the nuclear pores of Hela cells.
R4C8 works in immuno-cytochemistry very well.
|Restrictions||For Research Use only|
HandlingProduct Details anti-NUP153 Antibody Target Details NUP153 Application Details References for anti-NUP153 antibody (ABIN2452062) Images back to top
|Buffer||PBS, 50 % glycerol|
|Storage Comment||Upon receipt aliquot and store at -20 C|
References for anti-NUP153 antibody (ABIN2452062)Product Details anti-NUP153 Antibody Target Details NUP153 Application Details Handling Images back to top
|Product cited in:||
Lim, Fahrenkrog, Köser, Schwarz-Herion, Deng, Aebi: "Nanomechanical basis of selective gating by the nuclear pore complex." in: Science (New York, N.Y.), Vol. 318, Issue 5850, pp. 640-3, 2007
Ullman, Shah, Powers, Forbes: "The nucleoporin nup153 plays a critical role in multiple types of nuclear export." in: Molecular biology of the cell, Vol. 10, Issue 3, pp. 649-64, 1999
ImagesProduct Details anti-NUP153 Antibody Target Details NUP153 Application Details Handling References for anti-NUP153 antibody (ABIN2452062) back to top