Chemokine (C-C Motif) Ligand 12 (Ccl12) Protein

Details for Product No. ABIN1004916
Protein Name
Origin
Mouse (Murine)
17
Source
Escherichia coli (E. coli)
14
1
1
Protein Type
Recombinant
Options
Characteristics Recombinant Mouse Monocyte Chemotactic Protein 5 (CCL12). Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-50.0 ng/mL.
Purity > 99 % (determined by SDS-PAGE and HPLC analysis).
Sterility Sterile filtered
Endotoxin Level < 0.1 ng per µg (1EU/µg) of rMu MCP-5.
Protein Name
Background The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-5 is a 9.3 kDa protein containing 82 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Molecular Weight 9.3 kDa
Pathways Cellular Response to Molecule of Bacterial Origin
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please Note: Always centrifuge product briefly before opening the vial. Reconstitute in sterile, ultra-pure water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other aqueous buffers and stored at -20°C for future use.
Buffer Lyophilized from a sterile-filtered solution with no additives.
Preservative Without preservative
Storage -20 °C
Storage Comment The lyophilized powder, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted MCP-5 should be used immediately or stored in undiluted working aliquots at -20°C. Avoid repeated freeze / thaw cycles.