SDF1 beta Protein

Catalog No. ABIN1005059

Product Details

Target: SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))

Protein Type: Recombinant

Origin: Rat

Source: Escherichia coli (E. coli)

Characteristics: Recombinant Rat Stromal Cell Derived Factor 1-beta (CXCL12). Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 100.0-150.0 ng/mL.

Purity: > 97 % (determined by SDS-PAGE and HPLC analysis)

Sterility: Sterile filtered

Endotoxin Level: < 0.1 ng per µg of rRa SDF-1 beta (1EU/µg).

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please Note: Always centrifuge product before opening vial. The lyophilized protein should be reconstituted with distilled, sterile water to a concentration of 0.1-1.0 mg/mL. For further dilution, carrier protein (0.1% BSA or HSA) should be added to avoid loss of bioactivity.

Buffer: Lyophilized from a sterile-filtered concentrated protein solution containing 20 mM phosphate buffer (pH 7.4) and 0.15 M NaCl.

Storage: -20 °C

Storage Comment: The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted protein should be used immediately or stored long-term in undiluted working aliquots at -20°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles.

Target Details

Target: SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))

Alternative Name: SDF-1 beta/cxcl12 (SDF1b Products)

Synonyms: Pbsf Protein, Scyb12 Protein, Sdf1 Protein, Tlsf Protein, Tpar1 Protein, sdf1a Protein, SDF-1 Protein, chemokine (C-X-C motif) ligand 12 Protein, C-X-C motif chemokine ligand 12 Protein, Cxcl12 Protein, cxcl12 Protein, CXCL12 Protein

Background: SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1 alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant rat SDF-1 beta is an 8.4 kDa protein containing 72 amino acid residues.

Molecular Weight: 8.4 kDa