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HMGB1 Protein (AA 1-215) (His tag)

HMGB1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Catalog No. ABIN1079871
  • Target See all HMGB1 Proteins
    HMGB1 (High Mobility Group Box 1 (HMGB1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-215
    Origin
    • 27
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Source
    • 22
    • 12
    • 9
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HMGB1 protein is labelled with His tag.
    Application
    Western Blotting (WB), SDS-PAGE (SDS), Immunogen (Imm), Positive Control (PC)
    Sequence
    Met1-Glu215
    Characteristics
    Met1-Glu215 with N-terminal His-Tag.
    Purity
    > 90 %
    Top Product
    Discover our top product HMGB1 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Isoelectric Point:5.6

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4, containing 0.01 % SKL, 1 mM DTT, 5 % Trehalose and Proclin300.
    Preservative
    ProClin
    Storage
    4 °C,-80 °C
    Storage Comment
    Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
    Expiry Date
    12 months
  • Zhang, Chen, Feng, Shan, Zheng, Wang, Lu, Fan, Sun, Wu, Li, Hu, Wang, Zhang, Zheng: "FBXW7 suppresses HMGB1-mediated innate immune signaling to attenuate hepatic inflammation and insulin resistance in a mouse model of nonalcoholic fatty liver disease." in: Molecular medicine (Cambridge, Mass.), Vol. 25, Issue 1, pp. 29, (2020) (PubMed).

    Liu, Yu, Chen, Sun, Li, Huang, Nie, Wang, Zhang, Gong, Ren: "Hesperidin ameliorates lipopolysaccharide-induced acute lung injury in mice by inhibiting HMGB1 release." in: International immunopharmacology, Vol. 25, Issue 2, pp. 370-6, (2015) (PubMed).

    Ruzzenente, Iacono, Conci, Bertuzzo, Salvagno, Ruzzenente, Campagnaro, Valdegamberi, Pachera, Bagante, Guglielmi: "A novel serum marker for biliary tract cancer: diagnostic and prognostic values of quantitative evaluation of serum mucin 5AC (MUC5AC)." in: Surgery, Vol. 155, Issue 4, pp. 633-9, (2014) (PubMed).

  • Target
    HMGB1 (High Mobility Group Box 1 (HMGB1))
    Alternative Name
    High Mobility Group Protein 1 (HMGB1 Products)
    Synonyms
    HMG1 Protein, HMG3 Protein, SBP-1 Protein, DEF Protein, HMG-1 Protein, Hmg1 Protein, amphoterin Protein, p30 Protein, hmgb1 Protein, ik:tdsubc_1a5 Protein, wu:fb23c02 Protein, xx:tdsubc_1a5 Protein, zgc:56110 Protein, zgc:77104 Protein, hmg-1 Protein, hmg3 Protein, sbp-1 Protein, hmg1 Protein, HMGB1 Protein, Ac2-008 Protein, high mobility group box 1 Protein, high-mobility group box 1 Protein, high mobility group box 1a Protein, high mobility group box 1 L homeolog Protein, high mobility group protein B1 Protein, HMGB1 Protein, Hmgb1 Protein, hmgb1 Protein, hmgb1a Protein, hmgb1.L Protein, LOC100359149 Protein
    Background
    HMG1, HMG3, SBP1, Sulfoglucuronyl Carbohydrate Binding Protein, Amphoterin, High Mobility Group Box 1 Protein
    Molecular Weight
    26.4 kDa
    UniProt
    P63158
    Pathways
    p53 Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
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