Annexin a1 Protein (AA 2-346)

Catalog No. ABIN1096008

Product Details

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Protein Type: Recombinant

Protein Characteristics: AA 2-346

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human Annexin A1/ANXA1

Sequence: AMVSEFLKQA WFIENEEQEY VQTVKSSKGG PGSAVSPYPT FNPSSDVAAL HKAIMVKGVD EATIIDILTK RNNAQRQQIK AAYLQETGKP LDETLKKALT GHLEEVVLAL LKTPAQFDAD ELRAAMKGLG TDEDTLIEIL ASRTNKEIRD INRVYREELK RDLAKDITSD TSGDFRNALL SLAKGDRSED FGVNEDLADS DARALYEAGE RRKGTDVNVF NTILTTRSYP QLRRVFQKYT KYSKHDMNKV LDLELKGDIE KCLTAIVKCA TSKPAFFAEK LHQAMKGVGT RHKALIRIMV SRSEIDMNDI KAFYQKMYGI SLCQAILDET KGDYEKILVA LCGGN

Characteristics: Recombinant Human Annexin A1/ANXA1 is produced with our E. coli expression system. The target protein is expressed with sequence (Ala2-Asn346) of Human ANXA1.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: Annexin-A1 (ANXA1 Products)

Synonyms: anx1a Protein, anxa1 Protein, wu:fa01d11 Protein, wu:fa05d11 Protein, wu:fk69h01 Protein, MGC64363 Protein, anx1 Protein, lpc1 Protein, MGC89164 Protein, ANXA1 Protein, ANX1 Protein, LPC1 Protein, p35 Protein, Anx-1 Protein, Anx-A1 Protein, C430014K04Rik Protein, Lpc-1 Protein, Lpc1 Protein, Anx1 Protein, annexin A1a Protein, annexin A1 Protein, annexin A1 L homeolog Protein, Annexin A1 Protein, anxa1a Protein, anxa1 Protein, anxa1.L Protein, ANXA1 Protein, LOC100335033 Protein, Anxa1 Protein

Background: Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity. Annexin A1 also has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis, and tumorigenesis and cancer development. ANXA1 is strongly expressed on the cell membrane and occasionally in the cytoplasm of tumor cells in 97% of samples from patients with hairy cell leukemia.
Alternative Names: Annexin A1, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Phospholipase A2 Inhibitory Protein, p35

Molecular Weight: 38.58 kDa

UniProt: P04083

Pathways: Hormone Transport