ANXA6 Protein (AA 2-673) (His tag)

Catalog No. ABIN1096020

Product Details

Target: ANXA6 (Annexin A6 (ANXA6))

Protein Type: Recombinant

Protein Characteristics: AA 2-673

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ANXA6 protein is labelled with His tag.

Purpose: Recombinant Human Annexin A6/ANXA6 (C-6His)

Sequence: AKPAQGAKYR GSIHDFPGFD PNQDAEALYT AMKGFGSDKE AILDIITSRS NRQRQEVCQS YKSLYGKDLI ADLKYELTGK FERLIVGLMR PPAYCDAKEI KDAISGIGTD EKCLIEILAS RTNEQMHQLV AAYKDAYERD LEADIIGDTS GHFQKMLVVL LQGTREEDDV VSEDLVQQDV QDLYEAGELK WGTDEAQFIY ILGNRSKQHL RLVFDEYLKT TGKPIEASIR GELSGDFEKL MLAVVKCIRS TPEYFAERLF KAMKGLGTRD NTLIRIMVSR SELDMLDIRE IFRTKYEKSL YSMIKNDTSG EYKKTLLKLS GGDDDAAGQF FPEAAQVAYQ MWELSAVARV ELKGTVRPAN DFNPDADAKA LRKAMKGLGT DEDTIIDIIT HRSNVQRQQI RQTFKSHFGR DLMTDLKSEI SGDLARLILG LMMPPAHYDA KQLKKAMEGA GTDEKALIEI LATRTNAEIR AINEAYKEDY HKSLEDALSS DTSGHFRRIL ISLATGHREE GGENLDQARE DAQVAAEILE IADTPSGDKT SLETRFMTIL CTRSYPHLRR VFQEFIKMTN YDVEHTIKKE MSGDVRDAFV AIVQSVKNKP LFFADKLYKS MKGAGTDEKT LTRIMVSRSE IDLLNIRREF IEKYDKSLHQ AIEGDTSGDF LKALLALCGG EDLEHHHHHH

Characteristics: Recombinant Human Annexin A6/ANXA6 is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Asp673) of Human ANXA6.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: ANXA6 (Annexin A6 (ANXA6))

Alternative Name: annexin-a6 (ANXA6 Products)

Synonyms: ANX6 Protein, CBP68 Protein, AW107198 Protein, Anx6 Protein, AnxVI Protein, Cabm Protein, Camb Protein, CPB-II Protein, anx6 Protein, cbp68 Protein, ANXA6 Protein, DKFZp459M247 Protein, anxa6 Protein, annexin A6 Protein, annexin A6 L homeolog Protein, ANXA6 Protein, Anxa6 Protein, anxa6 Protein, anxa6.L Protein

Background: Annexin A6 (ANAX6) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A6 is a secreted protein and locates on the cell surface. Annexin A6 contains 8 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA6 is involved in the regulation of the release of Ca2+ from intracellular stores and may be associated with CD21. In addition, ANXA6 has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
Alternative Names: Annexin A6, 67 kDa Calelectrin, Annexin VI, Annexin-6, Calphobindin-II, CPB-II, Chromobindin-20, Lipocortin VI, Protein III, p68, p70, ANXA6, ANX6

Molecular Weight: 76.9 kDa

UniProt: P08133