BTN1A1 Protein (AA 27-242) (His tag)

Catalog No. ABIN1096152

Product Details

Target: BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))

Protein Type: Recombinant

Protein Characteristics: AA 27-242

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This BTN1A1 protein is labelled with His tag.

Purpose: Recombinant Human Butyrophilin 1A1/BTN1A1 (C-6His)

Sequence: APFDVIGPPE PILAVVGEDA ELPCRLSPNA SAEHLELRWF RKKVSPAVLV HRDGREQEAE QMPEYRGRAT LVQDGIAKGR VALRIRGVRV SDDGEYTCFF REDGSYEEAL VHLKVAALGS DPHISMQVQE NGEICLECTS VGWYPEPQVQ WRTSKGEKFP STSESRNPDE EGLFTVAASV IIRDTSAKNV SCYIQNLLLG QEKKVEISIP ASSLPRVDHH HHHH

Characteristics: Recombinant Human Butyrophilin Subfamily 1 Member A1/BTN1A1 produced by transfected human cells is a secreted protein with sequence (Ala27-Arg242) of Human BTN1A1 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))

Alternative Name: btn1a1 (BTN1A1 Products)

Synonyms: BT Protein, BTN Protein, Btn Protein, BTN1A1 Protein, TVC Protein, butyrophilin subfamily 1 member A1 Protein, butyrophilin, subfamily 1, member A1 Protein, zgc:162154 Protein, BTN1A1 Protein, Btn1a1 Protein, btn1a1 Protein, zgc:162154 Protein

Sub Type: Fusionprotein

Background: Butyrophilin Subfamily 1 Member A1 (BTN1A1) is the major protein associated with fat droplets in the milk. It belongs the immunoglobulin superfamily. BTN1A1 acts as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. It is localized to the major histocompatibility complex (MHC) class I region of 6p. It may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. It is shown that BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Alternative Names: Butyrophilin Subfamily 1 Member A1, BT, BTN1A1, BTN

Molecular Weight: 24.98 kDa

UniProt: Q13410

Pathways: Activated T Cell Proliferation