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Cathepsin L2 Protein (CTSL2) (AA 18-334) (His tag)

CTSL2 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1096248
  • Target See all Cathepsin L2 (CTSL2) Proteins
    Cathepsin L2 (CTSL2)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 18-334
    Origin
    • 8
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Cathepsin L2 protein is labelled with His tag.
    Purpose
    Recombinant Human Cathepsin L2/CTSL2 (C-6His)
    Sequence
    VPKFDQNLDT KWYQWKATHR RLYGANEEGW RRAVWEKNMK MIELHNGEYS QGKHGFTMAM NAFGDMTNEE FRQMMGCFRN QKFRKGKVFR EPLFLDLPKS VDWRKKGYVT PVKNQKQCGS CWAFSATGAL EGQMFRKTGK LVSLSEQNLV DCSRPQGNQG CNGGFMARAF QYVKENGGLD SEESYPYVAV DEICKYRPEN SVANDTGFTV VAPGKEKALM KAVATVGPIS VAMDAGHSSF QFYKSGIYFE PDCSSKNLDH GVLVVGYGFE GANSNNSKYW LVKNSWGPEW GSNGYVKIAK DKNNHCGIAT AASYPNVVDH HHHHH
    Characteristics

    Recombinant Human Cathepsin L2/CTSL2 (C-6His)

    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CTSL2 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    -80 °C
    Storage Comment
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Cathepsin L2 (CTSL2)
    Alternative Name
    Cathepsin L2 (CTSL2 Products)
    Synonyms
    CATL2 Protein, CTSL2 Protein, CTSU Protein, CTSL Protein, CTSL1 Protein, ctsl2 Protein, LOC100232421 Protein, cathepsin V Protein, cathepsin V L homeolog Protein, cathepsin L Protein, CTSV Protein, ctsv.L Protein, ctsv Protein, CTSL Protein, Ctsv Protein
    Background
    Recombinant Human Cathepsin L2 produced by transfected human cells is a secreted protein with sequence (Val18-Val384) of Human CTSL2 fused with a polyhistidine tag at the C-terminus.
    Cathepsin L2 belongs to the Peptidase C1 family. Cathepsin L2 can be autocatalytically converted to the mature form as a proenzyme in lysosomes at pH=7.0. Cathepsin L2 cannot be expressed in normal mammary gland, colon and peritumoral tissue, but it can be expressed in breast carcinomas and colorectal tissues. These suggeats Cathepsin L2 may play a role in tumor processes. Cathepsin L2 is specifically expressed in the testis, thymus, and corneal epithelium.
    Molecular Weight
    36.69 kDa
    UniProt
    O60911
    Pathways
    Toll-Like Receptors Cascades
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