DHPS Protein (AA 1-369) (His tag)

Catalog No. ABIN1096524

Product Details

Target: DHPS (Deoxyhypusine Synthase (DHPS))

Protein Type: Recombinant

Protein Characteristics: AA 1-369

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This DHPS protein is labelled with His tag.

Purpose: Recombinant Human Deoxyhypusine Synthase/DHS (C-6His)

Sequence: MEGSLEREAP AGALAAVLKH SSTLPPESTQ VRGYDFNRGV NYRALLEAFG TTGFQATNFG RAVQQVNAMI EKKLEPLSQD EDQHADLTQS RRPLTSCTIF LGYTSNLISS GIRETIRYLV QHNMVDVLVT TAGGVEEDLI KCLAPTYLGE FSLRGKELRE NGINRIGNLL VPNENYCKFE DWLMPILDQM VMEQNTEGVK WTPSKMIARL GKEINNPESV YYWAQKNHIP VFSPALTDGS LGDMIFFHSY KNPGLVLDIV EDLRLINTQA IFAKCTGMII LGGGVVKHHI ANANLMRNGA DYAVYINTAQ EFDGSDSGAR PDEAVSWGKI RVDAQPVKVY ADASLVFPLL VAETFAQKMD AFMHEKNEDL EHHHHHH

Characteristics: Recombinant Human Deoxyhypusine Synthase/DHS is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asp369) of Human Deoxyhypusine Synthase.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 20 % Glycerol, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: DHPS (Deoxyhypusine Synthase (DHPS))

Alternative Name: Deoxyhypusine Synthase/DHS (DHPS Products)

Synonyms: MGC76269 Protein, zgc:56018 Protein, zgc:77325 Protein, wu:fb52g04 Protein, wu:fj48f12 Protein, zgc:111900 Protein, MGC82178 Protein, DDBDRAFT_0186679 Protein, DDBDRAFT_0266388 Protein, DDB_0186679 Protein, DDB_0266388 Protein, DHS Protein, DS Protein, MIG13 Protein, Dhs Protein, DYS Protein, EDA22 Protein, K18J17.7 Protein, K18J17_7 Protein, deoxyhypusine synthase Protein, embryo sac development arrest 22 Protein, deoxyhypusine synthase Protein, deoxyhypusine synthase S homeolog Protein, Deoxyhypusine synthase Protein, DHPS Protein, dhps Protein, dhps.S Protein, SHELL_RS05250 Protein, PF14_0125 Protein, CNJ02480 Protein, Tb10.70.4900 Protein, Tb927.1.870 Protein, MMAH_RS09430 Protein, TAGG_RS03310 Protein, TAGG_RS05175 Protein, Mesil_2448 Protein, Trad_0088 Protein, Igag_1842 Protein, Desac_0724 Protein, MZHIL_RS05480 Protein, MZHIL_RS05835 Protein, MZHIL_RS06250 Protein, Dhps Protein, DHS Protein

Background: Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Alternative Names: Deoxyhypusine Synthase, DHS, DHPS, DS

Molecular Weight: 42.04 kDa

UniProt: P49366