Ephrin B2 Protein (EFNB2) (AA 28-229) (His tag)
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- Target See all Ephrin B2 (EFNB2) Proteins
- Ephrin B2 (EFNB2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-229
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Ephrin B2 protein is labelled with His tag.
- Purpose
- Recombinant Human Ephrin-B2/EFNB2 (C-6His)
- Sequence
- IVLEPIYWNS SNSKFLPGQG LVLYPQIGDK LDIICPKVDS KTVGQYEYYK VYMVDKDQAD RCTIKKENTP LLNCAKPDQD IKFTIKFQEF SPNLWGLEFQ KNKDYYIIST SNGSLEGLDN QEGGVCQTRA MKILMKVGQD ASSAGSTRNK DPTRRPELEA GTNGRSSTTS PFVKPNPGSS TDGNSAGHSG NNILGSEVAL FAVDHHHHHH
- Characteristics
- Recombinant Human Ephrin-B2 produced by transfected human cells is a secreted protein with sequence (Ile28-Ala229) of Human EFNB2 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product EFNB2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- Ephrin B2 (EFNB2)
- Alternative Name
- ephrin-b2 (EFNB2 Products)
- Synonyms
- EFNB2 Protein, efnb2 Protein, ephrin-B2 Protein, htkl Protein, eplg5 Protein, htk-l Protein, lerk5 Protein, ephrinB2 Protein, efnb2a Protein, MGC68890 Protein, efnb2b Protein, ELF-2 Protein, Epl5 Protein, Eplg5 Protein, Htk-L Protein, LERK-5 Protein, Lerk5 Protein, NLERK-1 Protein, EPLG5 Protein, HTKL Protein, LERK5 Protein, ephrin B2 Protein, ephrin-B2 precursor Protein, ephrin B2 L homeolog Protein, ephrin B2 S homeolog Protein, EFNB2 Protein, efnb2 Protein, efnb2.L Protein, efnb2.S Protein, Efnb2 Protein
- Sub Type
- Fusionprotein
- Background
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Ephrin-B2 is a type I transmembrane protein and belongs the Ephrin family. It binds to the receptor tyrosine kinases, such as EPHA4, EPHB4 and EPHA3. Ephrin-B2 has been implicated in mediating developmental events, especially in the nervous system, erythropoiesis and tumour metastasis. Ligation of Ephrin-B2 with complementary EphB receptors on adjacent cells results in a combination of forward (EphB receptors) and reverse (Ephrin-B2) signalling, which is central to tissue development and remodelling functions. In addition, Ephrin-B2 may play a role in constraining the orientation of longitudinally projecting axons.
Alternative Names: Ephrin-B2, EPH-Related Receptor Tyrosine Kinase Ligand 5, LERK-5, HTK Ligand, HTK-L, EFNB2, EPLG5, HTKL, LERK5 - Molecular Weight
- 23.24 kDa
- UniProt
- P52799
- Pathways
- RTK Signaling, Regulation of Muscle Cell Differentiation
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