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Ephrin B2 Protein (EFNB2) (AA 28-229) (His tag)

EFNB2 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1096582
  • Target See all Ephrin B2 (EFNB2) Proteins
    Ephrin B2 (EFNB2)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 28-229
    Origin
    • 10
    • 7
    • 1
    Human
    Source
    • 6
    • 5
    • 3
    • 2
    • 2
    Human Cells
    Purification tag / Conjugate
    This Ephrin B2 protein is labelled with His tag.
    Purpose
    Recombinant Human Ephrin-B2/EFNB2 (C-6His)
    Sequence
    IVLEPIYWNS SNSKFLPGQG LVLYPQIGDK LDIICPKVDS KTVGQYEYYK VYMVDKDQAD RCTIKKENTP LLNCAKPDQD IKFTIKFQEF SPNLWGLEFQ KNKDYYIIST SNGSLEGLDN QEGGVCQTRA MKILMKVGQD ASSAGSTRNK DPTRRPELEA GTNGRSSTTS PFVKPNPGSS TDGNSAGHSG NNILGSEVAL FAVDHHHHHH
    Characteristics
    Recombinant Human Ephrin-B2 produced by transfected human cells is a secreted protein with sequence (Ile28-Ala229) of Human EFNB2 fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product EFNB2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    Ephrin B2 (EFNB2)
    Alternative Name
    ephrin-b2 (EFNB2 Products)
    Synonyms
    EFNB2 Protein, efnb2 Protein, ephrin-B2 Protein, htkl Protein, eplg5 Protein, htk-l Protein, lerk5 Protein, ephrinB2 Protein, efnb2a Protein, MGC68890 Protein, efnb2b Protein, ELF-2 Protein, Epl5 Protein, Eplg5 Protein, Htk-L Protein, LERK-5 Protein, Lerk5 Protein, NLERK-1 Protein, EPLG5 Protein, HTKL Protein, LERK5 Protein, ephrin B2 Protein, ephrin-B2 precursor Protein, ephrin B2 L homeolog Protein, ephrin B2 S homeolog Protein, EFNB2 Protein, efnb2 Protein, efnb2.L Protein, efnb2.S Protein, Efnb2 Protein
    Sub Type
    Fusionprotein
    Background
    Ephrin-B2 is a type I transmembrane protein and belongs the Ephrin family. It binds to the receptor tyrosine kinases, such as EPHA4, EPHB4 and EPHA3. Ephrin-B2 has been implicated in mediating developmental events, especially in the nervous system, erythropoiesis and tumour metastasis. Ligation of Ephrin-B2 with complementary EphB receptors on adjacent cells results in a combination of forward (EphB receptors) and reverse (Ephrin-B2) signalling, which is central to tissue development and remodelling functions. In addition, Ephrin-B2 may play a role in constraining the orientation of longitudinally projecting axons.
    Alternative Names: Ephrin-B2, EPH-Related Receptor Tyrosine Kinase Ligand 5, LERK-5, HTK Ligand, HTK-L, EFNB2, EPLG5, HTKL, LERK5
    Molecular Weight
    23.24 kDa
    UniProt
    P52799
    Pathways
    RTK Signaling, Regulation of Muscle Cell Differentiation
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