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IL1A Protein

IL1A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1096876
  • Target See all IL1A Proteins
    IL1A (Interleukin 1 alpha (IL1A))
    Protein Type
    Recombinant
    Origin
    • 18
    • 12
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 39
    • 13
    • 12
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Human Interleukin-1α/IL-1α
    Sequence
    SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA
    Characteristics
    Recombinant Human Interleukin-1alpha/IL-1alpha produced in E. coli is a single non-glycosylated polypeptide chain containing 159 amino acids with a molecular mass of 18 kDa.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product IL1A Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    IL1A (Interleukin 1 alpha (IL1A))
    Alternative Name
    IL-1-alpha (IL1A Products)
    Synonyms
    IL-1A Protein, IL1 Protein, IL1-ALPHA Protein, IL1F1 Protein, IL-6 Protein, Il-1a Protein, IL-1 alpha Protein, IL-1alpha Protein, L1A Protein, interleukin 1 alpha Protein, interleukin 6 Protein, IL1A Protein, IL6 Protein, Il1a Protein
    Background
    Interleukin-1 alpha (IL1alpha) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1alpha and IL1beta that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1alpha is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1alpha. IL1alpha possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.
    Alternative Names: Interleukin-1 Alpha, IL-1 Alpha, Hematopoietin-1, IL1A, IL1F1
    Molecular Weight
    18 kDa
    UniProt
    P01583
    Pathways
    NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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