MAX Protein (AA 1-151) (His tag)

Catalog No. ABIN1097137

Product Details

Target: MAX (MYC Associated Factor X (MAX))

Protein Type: Recombinant

Protein Characteristics: AA 1-151

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This MAX protein is labelled with His tag.

Purpose: Recombinant Human Myc-Associated Factor X/MAX (C-6His)

Sequence: MSDNDDIEVE SDADKRAHHN ALERKRRDHI KDSFHSLRDS VPSLQGEKAS RAQILDKATE YIQYMRRKNH THQQDIDDLK RQNALLEQQV RALEKARSSA QLQTNYPSSD NSLYTNAKGS TISAFDGGSD SSSESEPEEP QSRKKLRMEA SLEHHHHHH

Characteristics: Recombinant Human Myc-Associated Factor X/MAX is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ser151) of Human MAX.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 50 mM Imidazole, 250 mM NaCl, pH 8.5.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: MAX (MYC Associated Factor X (MAX))

Alternative Name: myc-associated-factor-x (MAX Products)

Synonyms: CG9648 Protein, Dmel\\CG9648 Protein, MAX Protein, bHLHd9 Protein, dMax Protein, dmax Protein, max Protein, bhlhd4 Protein, bhlhd5 Protein, bhlhd6 Protein, bhlhd7 Protein, bhlhd8 Protein, xmax2 Protein, xmax4 Protein, xmax Protein, AA960152 Protein, AI875693 Protein, bHLHd4 Protein, bHLHd5 Protein, bHLHd6 Protein, bHLHd7 Protein, bHLHd8 Protein, fa92b04 Protein, fb52a04 Protein, fb95h11 Protein, wu:fa92b04 Protein, wu:fb52a04 Protein, wu:fb95h11 Protein, zmax Protein, CG9648 gene product from transcript CG9648-RD Protein, MYC associated factor X L homeolog Protein, MYC associated factor X Protein, Max protein Protein, MYC associated factor X S homeolog Protein, myc associated factor X Protein, Max Protein, max.L Protein, MAX Protein, max Protein, max.S Protein

Background: Myc-Associated Factor X (MAX) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It contains 1 basic helix-loop-helix (bHLH) domain. It is found in the brain, heart, and lung at high levels while lower levels are seen in the liver, kidney, and skeletal muscle. MAX forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. It may repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.
Alternative Names: Protein Max, Class D Basic Helix-Loop-Helix Protein 4, bHLHd4, Myc-Associated Factor X, MAX, BHLHD4

Molecular Weight: 18.27 kDa

UniProt: P61244

Pathways: Mitotic G1-G1/S Phases