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NDRG1 Protein (AA 1-394) (His tag)

NDRG1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1097200
  • Target See all NDRG1 Proteins
    NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-394
    Origin
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This NDRG1 protein is labelled with His tag.
    Purpose
    Recombinant Human N-myc Downstream Regulated Gene 1/NDRG1/DRG-1CAP43 (N-6His)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MSREMQDVDL AEVKPLVEKG ETITGLLQEF DVQEQDIETL HGSVHVTLCG TPKGNRPVIL TYHDIGMNHK TCYNPLFNYE DMQEITQHFA VCHVDAPGQQ DGAASFPAGY MYPSMDQLAE MLPGVLQQFG LKSIIGMGTG AGAYILTRFA LNNPEMVEGL VLINVNPCAE GWMDWAASKI SGWTQALPDM VVSHLFGKEE MQSNVEVVHT YRQHIVNDMN PGNLHLFINA YNSRRDLEIE RPMPGTHTVT LQCPALLVVG DSSPAVDAVV ECNSKLDPTK TTLLKMADCG GLPQISQPAK LAEAFKYFVQ GMGYMPSASM TRLMRSRTAS GSSVTSLDGT RSRSHTSEGT RSRSHTSEGT RSRSHTSEGA HLDITPNSGA AGNSAGPKSM EVSC
    Characteristics
    Recombinant Human Protein NDRG1/NDRG1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Cys394) of Human NDRG1 fused with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product NDRG1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))
    Alternative Name
    NDRG1 (NDRG1 Products)
    Synonyms
    CAP43 Protein, CMT4D Protein, DRG-1 Protein, DRG1 Protein, GC4 Protein, HMSNL Protein, NDR1 Protein, NMSL Protein, PROXY1 Protein, RIT42 Protein, RTP Protein, TARG1 Protein, TDD5 Protein, Ndr1 Protein, Ndrl Protein, cap43 Protein, cmt4d Protein, drg1 Protein, gc4 Protein, hmsnl Protein, ndr1 Protein, ndrg1 Protein, nmsl Protein, proxy1 Protein, rit42 Protein, rtp Protein, targ1 Protein, tdd5 Protein, xndrg1 Protein, ndrg4 Protein, cb775 Protein, wu:fb60h02 Protein, zgc:63944 Protein, NDRG1 Protein, NON-RACE SPECIFIC DISEASE RESISTANCE PROTEIN Protein, non race-specific disease resistance 1 Protein, ndrg1-a Protein, ndrg1-b Protein, xNDRG1-A Protein, ndrg1l Protein, zgc:73047 Protein, N-myc downstream regulated 1 Protein, N-myc downstream regulated gene 1 Protein, N-myc downstream regulated 1 S homeolog Protein, N-myc downstream regulated 1a Protein, Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family Protein, N-myc downstream regulated 1 L homeolog Protein, N-myc downstream regulated 1b Protein, NDRG1 Protein, Ndrg1 Protein, ndrg1.S Protein, ndrg1 Protein, ndrg1a Protein, NDR1 Protein, ndrg1.L Protein, ndrg1b Protein
    Sub Type
    Fusionprotein
    Background
    Protein NDRG1 is a member of the N-Myc Downregulated Gene family, which is part of the alpha/beta Hydrolase superfamily. Protein NDRG1 is a cytoplasmic protein that is involved in stress responses, hormone responses, cell growth and differentiation. Protein NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Protein NDRG1 mutuations are reported to be the cause for hereditary motor and sensory neuropathy-Lom. Decreased NDRG1 expression in glioma is linked to tumor progression, overexpression of NDRG1 is connected to malignant status of esophageal cancer.
    Alternative Names: Protein NDRG1, Differentiation-Related Gene 1 Protein, DRG-1, N-myc Downstream-Regulated Gene 1 Protein, Nickel-Specific Induction Protein Cap43, Reducing Agents and Tunicamycin-Responsive Protein, RTP, Rit42, NDRG1, CAP43, DRG1, RTP
    Molecular Weight
    45 kDa
    UniProt
    Q92597
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