PVALB Protein (AA 2-110) (His tag)

Catalog No. ABIN1097298

Product Details

Target: PVALB (Parvalbumin (PVALB))

Protein Type: Recombinant

Protein Characteristics: AA 2-110

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PVALB protein is labelled with His tag.

Purpose: Recombinant Human Parvalbumin α/PVALB (C-6His)

Sequence: SMTDLLNAED IKKAVGAFSA TDSFDHKKFF QMVGLKKKSA DDVKKVFHML DKDKSGFIEE DELGFILKGF SPDARDLSAK ETKMLMAAGD KDGDGKIGVD EFSTLVAESL EHHHHHH

Characteristics: Recombinant Human Parvalbumin alpha/PVALB is produced with our E. coli expression system. The target protein is expressed with sequence (Ser2-Ser110) of Human PVALB.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: PVALB (Parvalbumin (PVALB))

Alternative Name: pvalb (PVALB Products)

Synonyms: D22S749 Protein, PV Protein, Parv Protein, Pva Protein, PALB1 Protein, pvalb1 Protein, MGC107903 Protein, parvalbumin Protein, parvalbumin, gene 1 Protein, parvalbumin, gene 1 S homeolog Protein, PVALB Protein, Pvalb Protein, pvalb.1 Protein, pvalb.1.S Protein

Background: Parvalbumin alpha (PVALB) is a member of the parvalbumin family. PVALB is a high affinity calcium ion-binding protein, with two EF hand domains. PVALB is structurally and functionally similar to calmodulin and troponin C, it can bind two calcium ions. Parvalbumin is thought to be involved in relaxation after contraction in muscle. Parvalbumin is expressed in a specific population of GABAergic interneurons, which are believed to have a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus.
Alternative Names: Parvalbumin Alpha, PVALB

Molecular Weight: 13.12 kDa

UniProt: P20472