PNLIPRP1 Protein (AA 18-467) (His tag)

Catalog No. ABIN1097352

Product Details

Target: PNLIPRP1 (Pancreatic Lipase-Related Protein 1 (PNLIPRP1))

Protein Type: Recombinant

Protein Characteristics: AA 18-467

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This PNLIPRP1 protein is labelled with His tag.

Purpose: Recombinant Human Pancreatic Lipase-Related Protein 1/PLRP1 (C-6His)

Sequence: KEVCYEDLGC FSDTEPWGGT AIRPLKILPW SPEKIGTRFL LYTNENPNNF QILLLSDPST IEASNFQMDR KTRFIIHGFI DKGDESWVTD MCKKLFEVEE VNCICVDWKK GSQATYTQAA NNVRVVGAQV AQMLDILLTE YSYPPSKVHL IGHSLGAHVA GEAGSKTPGL SRITGLDPVE ASFESTPEEV RLDPSDADFV DVIHTDAAPL IPFLGFGTNQ QMGHLDFFPN GGESMPGCKK NALSQIVDLD GIWAGTRDFV ACNHLRSYKY YLESILNPDG FAAYPCTSYK SFESDKCFPC PDQGCPQMGH YADKFAGRTS EEQQKFFLNT GEASNFARWR YGVSITLSGR TATGQIKVAL FGNKGNTHQY SIFRGILKPG STHSYEFDAK LDVGTIDKVK FLWNNNVINP TLPKVGATKI TVQKGEEKTV YNFCSEDTVR EDTLLTLTPC VDHHHHHH

Characteristics: Recombinant Human Pancreatic Lipase-Related Protein 1/PLRP1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Lys18-Cys467) of Human PNLIPRP1 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: PNLIPRP1 (Pancreatic Lipase-Related Protein 1 (PNLIPRP1))

Alternative Name: PLRP1 (PNLIPRP1 Products)

Synonyms: MGC83411 Protein, PNLIPRP1 Protein, Plrp1 Protein, PLRP1 Protein, pancreatic lipase-related protein 1 S homeolog Protein, pancreatic lipase related protein 1 Protein, pancreatic lipase-related protein 1 Protein, pnliprp1.S Protein, PNLIPRP1 Protein, Pnliprp1 Protein

Sub Type: Fusionprotein

Background: Pancreatic Lipase-Related Protein 1 (PNLIPRP1) belongs to the Lipase family within the AB hydrolase superfamily. PNLIPRP1 is a secreted protein and contains one PLAT domain. PNLIPRP1 is involved in lipid metabolic process, acting as a negative regulator of pancreatic lipase activity by competing with pancreatic lipase for colipase occupancy. PNLIPRP1 may play a role in inhibiting dietary triglyceride digestion, but it lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters.
Alternative Names: Pancreatic Lipase-Related Protein 1, PL-RP1, PNLIPRP1, PLRP1

Molecular Weight: 50.99 kDa

UniProt: P54315