PSPH Protein (AA 1-225) (His tag)
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- Target See all PSPH Proteins
- PSPH (Phosphoserine Phosphatase (PSPH))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-225
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PSPH protein is labelled with His tag.
- Purpose
- Recombinant Human Phosphoserine Phosphatase/PSP (C-6His)
- Sequence
- MVSHSELRKL FYSADAVCFD VDSTVIREEG IDELAKICGV EDAVSEMTRR AMGGAVPFKA ALTERLALIQ PSREQVQRLI AEQPPHLTPG IRELVSRLQE RNVQVFLISG GFRSIVEHVA SKLNIPATNV FANRLKFYFN GEYAGFDETQ PTAESGGKGK VIKLLKEKFH FKKIIMIGDG ATDMEACPPA DAFIGFGGNV IRQQVKDNAK WYITDFVELL GELEELEHHH HHH
- Characteristics
- Recombinant Human Phosphoserine Phosphatase/PSP is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Glu225) of Human PSPH.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PSPH Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM Tris, 250 mM NaCl, 50 mM Imidazole, pH 8.5 .
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- PSPH (Phosphoserine Phosphatase (PSPH))
- Alternative Name
- PSPase (PSPH Products)
- Synonyms
- PSP Protein, PSPHD Protein, AI480570 Protein, PSPase Protein, PSPH Protein, psph Protein, MGC78828 Protein, zgc:112414 Protein, DDBDRAFT_0183847 Protein, DDBDRAFT_0230054 Protein, DDB_0183847 Protein, DDB_0230054 Protein, phosphoserine phosphatase Protein, phosphoserine phosphatase L homeolog Protein, PSP; O-phosphoserine phosphohydrolase; PSPase Protein, phosphoserine phosphatase SerB Protein, BPI fold containing family A member 2 Protein, PSPH Protein, Psph Protein, psph.L Protein, psph Protein, serB Protein, serB-1 Protein, LOC5568588 Protein, PSP Protein, Svir_29300 Protein, MMAH_RS03435 Protein, BPIFA2 Protein
- Background
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Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.
Alternative Names: Phosphoserine Phosphatase, PSP, PSPase, L-3-Phosphoserine Phosphatase, O-Phosphoserine Phosphohydrolase, PSPH - Molecular Weight
- 26.07 kDa
- UniProt
- P78330
- Pathways
- Warburg Effect
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