TXNDC12 Protein (AA 27-168) (His tag)

Catalog No. ABIN1097634

Product Details

Target: TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))

Protein Type: Recombinant

Protein Characteristics: AA 27-168

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This TXNDC12 protein is labelled with His tag.

Purpose: Recombinant Human Thioredoxin Domain-Containing Protein 12/TXNDC12/ERp18 (C-6His)

Sequence: HNGLGKGFGD HIHWRTLEDG KKEAAASGLP LMVIIHKSWC GACKALKPKF AESTEISELS HNFVMVNLED EEEPKDEDFS PDGGYIPRIL FLDPSGKVHP EIINENGNPS YKYFYVSAEQ VVQGMKEAQE RLTGDAFRKK HLVDHHHHHH

Characteristics: Recombinant Human Thioredoxin Domain-Containing Protein 12/TXNDC12 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (His27-Leu168) of Human TXNDC12 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 10 % Glycerol, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))

Alternative Name: TXNDC12 (TXNDC12 Products)

Synonyms: AG1 Protein, AGR1 Protein, ERP16 Protein, ERP18 Protein, ERP19 Protein, PDIA16 Protein, TLP19 Protein, hAG-1 Protein, hTLP19 Protein, 0610040B21Rik Protein, ERp16 Protein, ERp19 Protein, RGD1305960 Protein, thioredoxin domain containing 12 Protein, thioredoxin domain containing 12 (endoplasmic reticulum) Protein, TXNDC12 Protein, Txndc12 Protein

Sub Type: Fusionprotein

Background: Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors. TXNDC12 is widely expressed in many tissues and contains one thioredoxin domain.
Alternative Names: Thioredoxin Domain-Containing Protein 12, Endoplasmic Reticulum Resident Protein 18, ER Protein 18, ERp18, Endoplasmic Reticulum Resident Protein 19, ER Protein 19, ERp19, Thioredoxin-Like Protein p19, hTLP19, TXNDC12, TLP19

Molecular Weight: 16.98 kDa

UniProt: O95881

Pathways: Cell RedoxHomeostasis