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GSTA4 Protein (His tag)

GSTA4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN1098254
  • Target See all GSTA4 Proteins
    GSTA4 (Glutathione S-Transferase alpha 4 (GSTA4))
    Protein Type
    Recombinant
    Origin
    • 6
    • 2
    • 2
    • 1
    Human
    Source
    • 6
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GSTA4 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product GSTA4 Protein
  • Comment

    Synonyms: glutathione S-transferase alpha 4, GSTA4-4, GTA4

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer, pH 8.0, 20% glycerol, 2 mM DTT, 100 mM NaCl
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    GSTA4 (Glutathione S-Transferase alpha 4 (GSTA4))
    Alternative Name
    GSTA4 (GSTA4 Products)
    Synonyms
    GSTA4-4 Protein, GTA4 Protein, gsta4-4 Protein, gta4 Protein, tGSTA4 Protein, GST5.7 Protein, mGsta4 Protein, glutathione S-transferase alpha 4 Protein, glutathione S-transferase alpha 4-like Protein, glutathione S-transferase alpha 4 S homeolog Protein, glutathione S-transferase 3 Protein, glutathione S-transferase, alpha 4 Protein, glutathione S-transferase A4 Protein, GSTA4 Protein, Gsta4 Protein, GSTA4L Protein, gsta4 Protein, gsta4.S Protein, LOC100341622 Protein
    Background
    GSTA4, also known as glutathione S-transferase A4, belongs to the GST superfamily. This enzyme is involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. GSTA4 shows very high activity with reactive carbonyl compounds such as alk-2-enals. GSTA4 is highly effective in catalyzing the conjugate addition of reduced glutathione to 4-hydroxynonenal, an important product of peroxidative degradation of arachidonic acid and a commonly used biomarker for oxidative damage in tissue. This enzyme is expressed at a high level in brain, placenta, and skeletal muscle and much lower in lung and liver. Recombinant human GSTA4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    28.3kDa (246aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_001503
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