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PTGR2 Protein (His tag)

PTGR2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN1098255
  • Target See all PTGR2 Proteins
    PTGR2 (Prostaglandin Reductase 2 (PTGR2))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PTGR2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product PTGR2 Protein
  • Comment

    Synonyms: Prostaglandin reductase 2, PGR2, ZADH1

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    PTGR2 (Prostaglandin Reductase 2 (PTGR2))
    Alternative Name
    PTGR2 (PTGR2 Products)
    Synonyms
    ZADH1 Protein, MGC146252 Protein, PGR2 Protein, 1810016I24Rik Protein, 9130222H03Rik Protein, 9630002F03Rik Protein, AI838763 Protein, B830026H24Rik Protein, PGR-2 Protein, PRG-2 Protein, Zadh1 Protein, prostaglandin reductase 2 Protein, prostaglandin reductase 2 S homeolog Protein, PTGR2 Protein, ptgr2 Protein, ptgr2.S Protein, Ptgr2 Protein
    Background
    PTGR2 belongs to the medium-chain dehydrogenase/reductase superfamily. PTGR2 catalyzes an NADPH-dependent reduction of the conjugated alpha,beta-unsaturated double bond of 15-keto-PGE(2), a key step in terminal inactivation of prostaglandins and suppression of PPARgamma-mediated adipocyte differentiation. Selective inhibition of PTGR2 may contribute to the improvement of insulin sensitivity with fewer side effects. Recombinant human PTGR2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    41.1 kDa (375aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_689657
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