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EIF4H Protein (His tag)

EIF4H Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN1098293
  • Target See all EIF4H Proteins
    EIF4H (Eukaryotic Translation Initiation Factor 4H (EIF4H))
    Protein Type
    Recombinant
    Origin
    • 7
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 3
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This EIF4H protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product EIF4H Protein
  • Comment

    Synonyms: Eukaryotic translation initiation factor 4H, eIF-4H, WBSCR1, WSCR1

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 50% glycerol, 2 mM DTT
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    EIF4H (Eukaryotic Translation Initiation Factor 4H (EIF4H))
    Alternative Name
    EIF4H (EIF4H Products)
    Synonyms
    wscr1 Protein, wbscr1 Protein, WBSCR1 Protein, Wbscr1 Protein, WSCR1 Protein, eIF-4H Protein, AU018978 Protein, D5Ertd355e Protein, E430026L18Rik Protein, Ef4h Protein, Wscr1 Protein, mKIAA0038 Protein, zgc:77282 Protein, eukaryotic translation initiation factor 4H Protein, eukaryotic translation initiation factor 4H L homeolog Protein, eukaryotic translation initiation factor 4h Protein, transaltion initiation factor Protein, Eukaryotic translation initiation factor 4H Protein, eif4h Protein, eif4h.L Protein, EIF4H Protein, Eif4h Protein, LOC733087 Protein, SJAG_03433 Protein, MGYG_07815 Protein, Tsp_06589 Protein, if4h Protein
    Background
    Eukaryotic translation initiation factor 4H, also known as EIF4H, is a 248 amino acid protein that localizes to the perinuclear region of the cytoplasm and is expressed as two isoforms, designated short and long. EIF4H induces the RNA-dependent ATP hydrolysis catalyzed by the initiation factors EIF4A and EIF4B. EIF4H was further shown to stimulate the initial rate and extent of EIF4A-mediated mRNA secondary structure unwinding. Defects in the gene encoding EIF4H are associated with Williams- Beuren syndrome (WBS), a rare developmental disorder characterized by cardiovascular and musculo-skeletal abnormalities. Recombinant human EIF4H protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    29.9 kDa (272aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_071496
    Pathways
    SARS-CoV-2 Protein Interactome
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