C4BPB Protein (His tag)
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- Target See all C4BPB Proteins
- C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This C4BPB protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product C4BPB Protein
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- Comment
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Synonyms: Complement component 4 binding protein, beta, C4BP
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.15 M NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))
- Alternative Name
- C4BPB (C4BPB Products)
- Synonyms
- C4BPB Protein, C4BP Protein, C4bp-ps1 Protein, complement component 4 binding protein beta Protein, complement component 4 binding protein, beta Protein, C4BPB Protein, C4bpb Protein
- Background
- C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain of this protein assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. Recombinant human C4BPB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 29.0kDa(260aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_000707
- Pathways
- Complement System
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