LIN28B Protein (His tag)
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- Target See all LIN28B Proteins
- LIN28B (Lin-28 Homolog B (LIN28B))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LIN28B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product LIN28B Protein
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- Comment
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Synonyms: Protein lin-28 homolog B, CSDD2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 10% glycerol, 2 mM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- LIN28B (Lin-28 Homolog B (LIN28B))
- Alternative Name
- Lin28B (LIN28B Products)
- Synonyms
- csdd2 Protein, LIN-28 Protein, CSDD2 Protein, 2810403D23Rik Protein, D030047M17Rik Protein, Lin-28.2 Protein, lin-28 homolog B Protein, lin-28 homolog B S homeolog Protein, lin-28 homolog B (C. elegans) Protein, LIN28B Protein, lin28b Protein, lin28b.S Protein, Lin28b Protein
- Background
- Lin28B belongs to the lin-28 family. LIN28 protein is a microRNA-binding protein that binds to and enhances the translation of the IGF-2 (insulin-like growth factor 2) mRNA. Lin28B is acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Recombinant human Lin28B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 29.5 kDa (273aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI Accession
- NP_001004317
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