TANK Protein (His tag)
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- Target See all TANK Proteins
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TANK protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product TANK Protein
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TRAF Family Member-Associated NFKB Activator (TANK) (AA 1-119) protein (GST tag)
TANK Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
TRAF Family Member-Associated NFKB Activator (TANK) (AA 1-448) protein (His tag)TANK Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
TRAF Family Member-Associated NFKB Activator (TANK) (AA 1-425) protein (Strep Tag)Crystallography grade TANK Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
TRAF Family Member-Associated NFKB Activator (TANK) (AA 1-448) protein (Strep Tag)Crystallography grade TANK Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
TRAF Family Member-Associated NFKB Activator (TANK) (AA 1-119), (partial) protein (GST tag)TANK Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
TRAF Family Member-Associated NFKB Activator (TANK) (AA 1-119), (partial) protein (His tag)TANK Origin: Human Host: Yeast Recombinant > 90 % SDS
TRAF Family Member-Associated NFKB Activator (TANK) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TANK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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Synonyms: TRAF family member-associated NFkappa-B activator isoform a, I-TRAF, TRAF2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 50% glycerol, 2 mM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- Alternative Name
- TANK (TANK Products)
- Synonyms
- I-TRAF Protein, ITRAF Protein, TRAF2 Protein, C86182 Protein, E430026L09Rik Protein, zgc:153048 Protein, i-traf Protein, tank Protein, traf2 Protein, TRAF family member associated NFKB activator Protein, TRAF family member-associated Nf-kappa B activator Protein, TRAF family member-associated NFKB activator Protein, TRAF family member associated NFKB activator L homeolog Protein, TANK Protein, Tank Protein, tank Protein, tank.L Protein
- Background
- TANK, also known as TRAF interacting protein, is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby proposing that this protein is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Overexpression of TANK inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and inhibits LMP1-mediated NF-kappa-B activation by blocking the association of TRAF2 with LMP1. Recombinant human TANK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 50.2 kDa (448aa)
- NCBI Accession
- NP_001186064
- Pathways
- p53 Signaling, TLR Signaling, Activation of Innate immune Response
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