IL12B Protein (His tag)
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- Target See all IL12B Proteins
- IL12B (Interleukin 12 beta (IL12B))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Hi-5 Cells
- Purification tag / Conjugate
- This IL12B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by using conventional chromatography.
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product IL12B Protein
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Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)
IL12B Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)IL12B Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)IL12B Origin: Human Host: Tobacco (Nicotiana benthamiana) Recombinant > 97 % by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue. WB, Imm
Interleukin 12 beta (IL12B) protein (His tag)IL12B Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interleukin 12 beta (IL12B) (AA 23-328) proteinIL12B Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS
Interleukin 12 beta (IL12B) (AA 229-328) protein (GST tag)IL12B Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)IL12B Origin: Human Host: Insect Cells Recombinant SDS
Interleukin 12 beta (IL12B) (AA 23-335) protein (His tag)Crystallography grade IL12B Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 12 beta (IL12B) (AA 23-328) protein (Fc Tag)IL12B Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Interleukin 12 beta (IL12B) (AA 23-328) (Active) protein (His tag)IL12B Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- Comment
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Synonyms: interleukin 12 subuit beta, CLMF, NKSF, CLMF2, NKSF2, IL-12B
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 20% glycerol, 100 mM NaCl, 0.1 MM PMSF
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- IL12B (Interleukin 12 beta (IL12B))
- Alternative Name
- IL12P40 (IL12B Products)
- Synonyms
- CLMF Protein, CLMF2 Protein, IL-12B Protein, NKSF Protein, NKSF2 Protein, p40 Protein, Il-12b Protein, Il12p40 Protein, Il-12p40 Protein, Il12 Protein, IL-12p40 Protein, IL-12 Protein, IL-12 p40 Protein, il12b Protein, il12p40.b Protein, zgc:152789 Protein, IL-12.p40 Protein, IL12p40 Protein, IL12B Protein, CLMF p40 Protein, interleukin 12B Protein, interleukin 12b Protein, interleukin 12Ba Protein, IL12B Protein, Il12b Protein, il12ba Protein
- Background
- IL12P40 (interleukin 12 subunit beta), also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40, belongs to the type I cytokine receptor family. This protein is a cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. Recombinant human IL12P40 protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography.
- Molecular Weight
- 35.8kDa (315aa)
- NCBI Accession
- NP_002178
- Pathways
- JAK-STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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