TDG Protein (His tag)
-
- Target See all TDG Proteins
- TDG (Thymine-DNA Glycosylase (TDG))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TDG protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TDG Protein
-
Thymine-DNA Glycosylase (TDG) (AA 312-409) protein (GST tag)
TDG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Thymine-DNA Glycosylase (TDG) (AA 1-410) protein (GST tag)TDG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Thymine-DNA Glycosylase (TDG) (AA 1-410) protein (Strep Tag)Crystallography grade TDG Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Thymine-DNA Glycosylase (TDG) (AA 1-421) protein (Strep Tag)Crystallography grade TDG Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
-
- Comment
-
Synonyms: Thymine-DNA glycosylase, G/T mismatch-specific thymine DNA glycosylase
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 Urea, 10% glycerol, 0.1 M NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
-
- Target
- TDG (Thymine-DNA Glycosylase (TDG))
- Alternative Name
- TDG (TDG Products)
- Synonyms
- 5-MCDG Protein, wu:fb44b11 Protein, zgc:110622 Protein, MGC82456 Protein, MGC89441 Protein, E130317C12Rik Protein, JZA-3 Protein, Jza1 Protein, hTDG Protein, thymine DNA glycosylase Protein, thymine DNA glycosylase, tandem duplicate 1 Protein, putative g/t mismatch-specific thymine DNA glycosylase Protein, G/T mismatch-specific thymine DNA glycosylase Protein, thymine DNA glycosylase S homeolog Protein, thymine-DNA glycosylase Protein, TDG Protein, tdg.1 Protein, Smp_149220 Protein, Tsp_05734 Protein, tdg.S Protein, tdg Protein, Tdg Protein
- Background
- Thymine-DNA glycosylase, also known as TDG, belongs to the TDG/mug DNA glycosylase family. TDG is a nuclear protein which corrects G/T mismatches to G/C pairs by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired thymin. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. Recombinant human TDG protein, fused to His-tag at N-terminus, was expressed in E.coli
- Molecular Weight
- 48.4 kDa (433aa)
- Pathways
- DNA Damage Repair, Chromatin Binding
-
