TPSAB1 Protein (His tag)
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- Target See all TPSAB1 Proteins
- TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TPSAB1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product TPSAB1 Protein
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- Comment
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Synonyms: Tryptase alpha/beta-1, TPS1, TPS2, TPSB1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4 M Urea
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
- Alternative Name
- TPSAB1 (TPSAB1 Products)
- Synonyms
- TPS1 Protein, TPS2 Protein, TPSB1 Protein, PMCT7 Protein, tpsab1 Protein, tryptaseB Protein, tryptaseC Protein, MMCP-7 Protein, Mcp-7 Protein, Mcp7 Protein, Mcpt7 Protein, rMCP-7 Protein, AV011504 Protein, MMCP-6 Protein, Mcp-6 Protein, Mcp6 Protein, Mcpt6 Protein, tryptase alpha/beta 1 Protein, tryptase Protein, tryptase beta 2 (gene/pseudogene) Protein, tryptase beta 2 Protein, TPSAB1 Protein, MCT7 Protein, tpsab1 Protein, TPSB2 Protein, Tpsab1 Protein, Tpsb2 Protein
- Background
- TPSAB1, also known as tryptase alpha/beta-1, is a tryptase that is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It is enzymatically active only as a heparin-stabilized tetramer, and it is resistant to all known an endogenous proteinase inhibitor. This protein has been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. Recombinant human TPSAB1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 30.1 kDa(270aa)
- NCBI Accession
- NP_003285
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