Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

DEDD Protein (His tag)

DEDD Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN7280134
  • Target See all DEDD Proteins
    DEDD (Death Effector Domain Containing (DEDD))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This DEDD protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product DEDD Protein
  • Comment

    Synonyms: Death effector domain-containing protein, CASP8IP1, DEDD1, DEFT, FLDED1, KE05

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    DEDD (Death Effector Domain Containing (DEDD))
    Alternative Name
    DEDD (DEDD Products)
    Synonyms
    CASP8IP1 Protein, DEDD1 Protein, DEFT Protein, FLDED1 Protein, Dedpro1 Protein, KE05 Protein, Deft Protein, death effector domain containing Protein, death effector domain-containing Protein, DEDD Protein, Dedd Protein
    Background
    Death effector domain-containing protein, also known as DEDD, is a cytoplasmic protein. It translocates to the nucleus during CD95-mediated apoptosis, where it localizes to nucleoli-like structures, activates caspase-6 and specifically inhibits RNA polymerase I-dependent transcription. The cell death activity of DEDD relates to its nuclear localization. DEDD is widely expressed in a variety of tissues, with highest levels in the testis. Overexpression of this gene was shown to induce weak apoptosis. Recombinant human DEDD protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Molecular Weight
    38.9 kDa (338aa)
    NCBI Accession
    NP_127491
You are here:
Support