TDP1 Protein (His tag)
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- Target See all TDP1 Proteins
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TDP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TDP1 Protein
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Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) protein (GST tag)
TDP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 121-218) protein (GST tag)TDP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) protein (Strep Tag)Crystallography grade TDP1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-609) protein (Strep Tag)Crystallography grade TDP1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) proteinTDP1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA, IP
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TDP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TDP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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Synonyms: Tyrosyl-DNA phosphodiesterase 1, FLJ11090, SCAN1, Tyr-DNA phosphodiesterase 1, Tyrosyl DNA phosphodiesterase 1, TDP-1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- Alternative Name
- TDP1 (TDP1 Products)
- Synonyms
- 2810481F14Rik Protein, 4921509N21Rik Protein, AI838772 Protein, AW493413 Protein, E430034L06Rik Protein, MLZ-501 Protein, SCAN1 Protein, tdp1 Protein, MGC83708 Protein, TDP1 Protein, F8M21.60 Protein, F8M21_60 Protein, tyrosyl-DNA phosphodiesterase 1 Protein, tyrosyl-DNA phosphodiesterase 1 Protein, tyrosyl-DNA Phosphodiesterase (Tdp1) Protein, tyrosyl-DNA phosphodiesterase 1 L homeolog Protein, tyrosyl-DNA phosphodiesterase-like protein Protein, TDP1 Protein, Tc00.1047053511191.10 Protein, Tdp1 Protein, tdp1.L Protein, tdp1 Protein, PTRG_11198 Protein, MCYG_02121 Protein, MGYG_03035 Protein
- Background
- Tyrosyl-DNA phosphodiesterase 1, also known as TDP1, is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. Recombinant human TDP1, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 35.8 kDa (318aa)
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