IL12 Protein

Catalog No. ABIN1112288

Product Details

Target: IL12 (Interleukin 12 (IL12))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Application: Biochemical Assay (BCA)

Sequence: p35 Subunit: RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNASp40 Subunit: IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLYENY TSSFFIRDII KPDPPKNLQL KPLKNSRQVE VSWEYPDTWS TPHSYFSLTF CVQVQGKSKR EKKDRVFTDK TSATVICRKN ASISVRAQDR YYSSSWSEWA SVPCS.

No Cross-Reactivity: Mouse (Murine), Monkey, Bacteria

Characteristics: The ED50 was determined by the induction of IFN-gamma from NK cells co-stimulated with IL-18 is less or equal to 1.0 ng/ml, corresponding to a specific activity of greater than or equal to 1 x 10^6 units/mg.

Purity: > 95 % as determined by SDS-PAGE analysis.

Sterility: 0.2 μm filtered

Endotoxin Level: Endotoxin: 1.EU/µg determined by LAL method.

Application Details

Comment:

Length: 503 AA

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: We recommended spin the vial shortly prior to opening to bring the contents to the bottom. Lyophilized hIL12 should be reconstituted in deionized water to 0,1-1 µg/mL to regain full activity. These stock solutions should be apportioned into working aliquots and stored at -20 °C. Further dilutions should be made in low endotoxin medium or buffered solution with FBS or tissue culture grade BSA.

Storage: -20 °C

Target Details

Target: IL12 (Interleukin 12 (IL12))

Alternative Name: IL-12 (IL12 Products)

Synonyms: CLMF Protein, CLMF2 Protein, IL-12B Protein, NKSF Protein, NKSF2 Protein, p40 Protein, Il-12b Protein, Il12p40 Protein, Il-12p40 Protein, Il12 Protein, IL-12p40 Protein, IL-12 Protein, LOC100217488 Protein, IL-12p35 Protein, Il-12a Protein, Ll12a Protein, p35 Protein, IL12p40 Protein, IL12B Protein, IL-12 p35 Protein, interleukin 12B Protein, interleukin 12A Protein, interleukin 12b Protein, interleukin 12a Protein, Interleukin 12 level Protein, IL12B Protein, IL12A Protein, Il12b Protein, Il12a Protein, IL12 Protein, il12a Protein

Molecular Weight: 75 kDa.

Pathways: JAK-STAT Signaling, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome