Lamin A/C Protein (LMNA) (AA 1-664) (GST tag)
(2 references)-
- Target See all Lamin A/C (LMNA) Proteins
- Lamin A/C (LMNA)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-664
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Origin
- Human
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Source
- Wheat germ
- Purification tag / Conjugate
- This Lamin A/C protein is labelled with GST tag.
- Application
- Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
- Purpose
- LMNA (Human) Recombinant Protein (P01)
- Sequence
- METPSQRRAT RSGAQASSTP LSPTRITRLQ EKEDLQELND RLAVYIDRVR SLETENAGLR LRITESEEVV SREVSGIKAA YEAELGDARK TLDSVAKERA RLQLELSKVR EEFKELKARN TKKEGDLIAA QARLKDLEAL LNSKEAALST ALSEKRTLEG ELHDLRGQVA KLEAALGEAK KQLQDEMLRR VDAENRLQTM KEELDFQKNI YSEELRETKR RHETRLVEID NGKQREFESR LADALQELRA QHEDQVEQYK KELEKTYSAK LDNARQSAER NSNLVGAAHE ELQQSRIRID SLSAQLSQLQ KQLAAKEAKL RDLEDSLARE RDTSRRLLAE KEREMAEMRA RMQQQLDEYQ ELLDIKLALD MEIHAYRKLL EGEEERLRLS PSPTSQRSRG RASSHSSQTQ GGGSVTKKRK LESTESRSSF SQHARTSGRV AVEEVDEEGK FVRLRNKSNE DQSMGNWQIK RQNGDDPLLT YRFPPKFTLK AGQVVTIWAA GAGATHSPPT DLVWKAQNTW GCGNSLRTAL INSTGEEVAM RKLVRSVTVV EDDEDEDGDD LLHHHHGSHC SSSGDPAEYN LRSRTVLCGT CGQPADKASA SGSGAQVGGP ISSGSSASSV TVTRSYRSVG GSGGGSFGDN LVTRSYLLGN SSPRTQSPQN CSIM
- Characteristics
- Human LMNA full-length ORF ( NP_733821.1, 1 a.a. - 664 a.a.) recombinant protein with GST-tag at N-terminal.
- Purification
- in vitro wheat germ expression system
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Lamin A/C (LMNA) (AA 26-198) protein (His tag)
LMNA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Lamin A/C (LMNA) (AA 1-646) protein (His tag)Crystallography grade LMNA Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lamin A/C (LMNA) (AA 1-647) protein (His tag)Crystallography grade LMNA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lamin A/C (LMNA) (AA 1-661) protein (His tag)Crystallography grade LMNA Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lamin A/C (LMNA) (AA 1-662) protein (His tag)Crystallography grade LMNA Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lamin A/C (LMNA) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)LMNA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue. - Restrictions
- For Research Use only
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- Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
- Handling Advice
- Aliquot to avoid repeated freezing and thawing.
- Storage
- -80 °C
- Storage Comment
- Best use within three months from the date of receipt of this protein.
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: "A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C." in: PLoS ONE, Vol. 7, Issue 1, pp. e30376, (2012) (PubMed).
: "Proteomic identification of Hsp70 as a new Plk1 substrate in arsenic trioxide-induced mitotically arrested cells." in: Proteomics, Vol. 11, Issue 22, pp. 4331-45, (2011) (PubMed).
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: "A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C." in: PLoS ONE, Vol. 7, Issue 1, pp. e30376, (2012) (PubMed).
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- Target
- Lamin A/C (LMNA)
- Alternative Name
- LMNA (LMNA Products)
- Synonyms
- CDCD1 Protein, CDDC Protein, CMD1A Protein, CMT2B1 Protein, EMD2 Protein, FPL Protein, FPLD Protein, FPLD2 Protein, HGPS Protein, IDC Protein, LDP1 Protein, LFP Protein, LGMD1B Protein, LMN1 Protein, LMNC Protein, LMNL1 Protein, PRO1 Protein, Dhe Protein, 2459 Protein, 74/76 Protein, CG6944 Protein, D5 Protein, DM[[O]] Protein, Dm Protein, Dm(0) Protein, Dm0 Protein, Dm1 Protein, Dm2 Protein, DmLamin Protein, DmO Protein, Dm[[0]] Protein, Dm[[1]] Protein, Dm[[2]] Protein, Dm[[mit]] Protein, Dm[[o]] Protein, Dmel\\CG6944 Protein, Dmo Protein, LAM Protein, Lam Dm[[0]] Protein, Lam(Dm0) Protein, LamDm[[0]] Protein, LamDm[[o]] Protein, Lam[[Dm0]] Protein, Lamin Dm[[0]] Protein, jf27 Protein, l(2)04643 Protein, l(2)25Ec Protein, l(2)gdh-7 Protein, l(2)gdh7 Protein, l(2)jf27 Protein, lam Protein, lamDm0 Protein, lamDm[[0]] Protein, lamin Protein, lamin Dm0 Protein, lamin Dm[[0]] Protein, misg Protein, nlam Protein, cb948 Protein, fk66d12 Protein, wu:fk66d12 Protein, lmna-A Protein, fpl Protein, idc Protein, lfp Protein, cddc Protein, emd2 Protein, fpld Protein, hgps Protein, ldp1 Protein, lmn1 Protein, lmnc Protein, pro1 Protein, cdcd1 Protein, cmd1a Protein, cmt2b1 Protein, lgmd1b Protein, Lamin-A Protein, lamin-L(III)-like Protein, lamin A/C Protein, lamin A Protein, Lamin Protein, lamin A/C L homeolog Protein, lamin-L(III)-like Protein, LMNA Protein, Lmna Protein, Lam Protein, lmna Protein, lmna.L Protein, LMINA Protein
- Background
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Full Gene Name: lamin A/C
Synonyms: CDCD1,CDDC,CMD1A,CMT2B1,EMD2,FPL,FPLD,HGPS,IDC,LDP1,LFP,LGMD1B,LMN1,LMNC,PRO1 - Gene ID
- 4000
- NCBI Accession
- NM_170707
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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