Retinoic Acid Receptor alpha Protein (AA 1-462) (GST tag)

Catalog No. ABIN1317431

Product Details

Target: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Protein Type: Recombinant

Protein Characteristics: AA 1-462

Origin: Human

Source: Wheat germ

Purification tag / Conjugate: This Retinoic Acid Receptor alpha protein is labelled with GST tag.

Application: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Purpose: RARA (Human) Recombinant Protein (P01)

Sequence: MASNSSSCPT PGGGHLNGYP VPPYAFFFPP MLGGLSPPGA LTTLQHQLPV SGYSTPSPAT IETQSSSSEE IVPSPPSPPP LPRIYKPCFV CQDKSSGYHY GVSACEGCKG FFRRSIQKNM VYTCHRDKNC IINKVTRNRC QYCRLQKCFE VGMSKESVRN DRNKKKKEVP KPECSESYTL TPEVGELIEK VRKAHQETFP ALCQLGKYTT NNSSEQRVSL DIDLWDKFSE LSTKCIIKTV EFAKQLPGFT TLTIADQITL LKAACLDILI LRICTRYTPE QDTMTFSDGL TLNRTQMHNA GFGPLTDLVF AFANQLLPLE MDDAETGLLS AICLICGDRQ DLEQPDRVDM LQEPLLEALK VYVRKRRPSR PHMFPKMLMK ITDLRSISAK GAERVITLKM EIPGSMPPLI QEMLENSEGL DTLSGQPGGG GRDGGGLAPP PGSCSPSLSP SSNRSSPATH SP

Characteristics: Human RARA full-length ORF ( AAH08727, 1 a.a. - 462 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Rondina, Freitag, Pluthero, Kahr, Rowley, Kraiss, Franks, Zimmerman, Weyrich, Schwertz: "Non-genomic activities of retinoic acid receptor alpha control actin cytoskeletal events in human platelets." in: Journal of thrombosis and haemostasis : JTH, Vol. 14, Issue 5, pp. 1082-94, (2016) (PubMed).

Schulz, Paus, Frey, Schmid, Kohl, Mennerich, Winkler, Gillardon: "Leucine-rich repeat kinase 2 modulates retinoic acid-induced neuronal differentiation of murine embryonic stem cells." in: PLoS ONE, Vol. 6, Issue 6, pp. e20820, (2011) (PubMed).

Target Details

Target: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Alternative Name: RARA (RARA Products)

Background: Full Gene Name: retinoic acid receptor, alpha
Synonyms: NR1B1,RAR

Gene ID: 5914

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins