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FAS Protein (AA 26-170) (Fc Tag)

FAS Origin: Human, Mouse Host: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS Active
Catalog No. ABIN1344149
  • Target See all FAS Proteins
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 26-170
    Origin
    • 26
    • 10
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Source
    • 21
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This FAS protein is labelled with Fc Tag.
    Application
    SDS-PAGE (SDS)
    Specificity
    Binds human and mouse FasL.
    Cross-Reactivity
    Human, Mouse (Murine)
    Characteristics
    The Fc portion of human IgG1 is fused to the C-terminus of human Fas (aa 26-170).
    Purity
    >95 % (SDS-PAGE)
    Endotoxin Level
    <0.01EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product FAS Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Blocks the binding of FasL to Fas.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 50 μL sterile water.
    Concentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Expiry Date
    6 months
  • Target
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Alternative Name
    Fas (FAS Products)
    Synonyms
    ALPS1A Protein, APO-1 Protein, APT1 Protein, CD95 Protein, FAS1 Protein, FASTM Protein, TNFRSF6 Protein, AI196731 Protein, APO1 Protein, TNFR6 Protein, Tnfrsf6 Protein, lpr Protein, Fas cell surface death receptor Protein, Fas (TNF receptor superfamily member 6) Protein, FAS Protein, Fas Protein, fas Protein
    Background
    FasL is a cytokine that binds to Fas/TNFRSF6, a receptor that transduces the apoptotic signal into cells. FasL is involved in cytotoxic T cell mediated apoptosis and in T cell development.
    Molecular Weight
    ~47kDa (SDS-PAGE)
    UniProt
    P25445
    Pathways
    p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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