BCMA Protein (AA 1-46, Extracellular Domain) (Fc Tag)
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- Target See all BCMA (TNFRSF17) Proteins
- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Extracellular Domain, AA 1-46
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Origin
- Human, Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BCMA protein is labelled with Fc Tag.
- Application
- SDS-PAGE (SDS)
- Specificity
- Binds mouse and human BAFF and APRIL.
- Cross-Reactivity
- Human, Mouse (Murine)
- Characteristics
- The extracellular domain of mouse BCMA (aa 1-46) is fused at the C-terminus to the Fc portion of human IgG1.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFRSF17 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Blocks the binding of mouse BAFF and human APRIL to their receptors BCMA and TACI.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 50 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
- Alternative Name
- BCMA (TNFRSF17 Products)
- Synonyms
- TNFRSF17 Protein, BCM Protein, BCMA Protein, CD269 Protein, TNFRSF13A Protein, Tnfrsf13 Protein, Tnfrsf13a Protein, TNF receptor superfamily member 17 Protein, tumor necrosis factor receptor superfamily, member 17 Protein, Tnfrsf17 Protein, TNFRSF17 Protein
- Background
- BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. It's downstream signaling is dependent on NF-kappaB and JNK.
- Molecular Weight
- ~35kDa (SDS-PAGE)
- UniProt
- O88472
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