Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Notch1 Protein (AA 19-488, Extracellular Domain) (Fc Tag)

NOTCH1 Origin: Mouse Host: CHO Cells Recombinant >95 % (SDS-PAGE) SDS
Catalog No. ABIN1344231
  • Target See all Notch1 (NOTCH1) Proteins
    Notch1 (NOTCH1) (Notch 1 (NOTCH1))
    Protein Type
    Recombinant
    Protein Characteristics
    Extracellular Domain, AA 19-488
    Origin
    • 8
    • 7
    Mouse
    Source
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    CHO Cells
    Purification tag / Conjugate
    This Notch1 protein is labelled with Fc Tag.
    Application
    SDS-PAGE (SDS)
    Specificity
    Binds to mouse DLL4.
    Cross-Reactivity
    Mouse (Murine)
    Characteristics
    The extracellular domain of mouse Notch1 (aa 19-488) (12 epidermal growth factor-like (EGF) repeats) is fused at the C-terminus to the Fc portion of human IgG1.
    Purity
    >95 % (SDS-PAGE)
    Endotoxin Level
    <0.1EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product NOTCH1 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 50 μL sterile water.
    Concentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Expiry Date
    6 months
  • Target
    Notch1 (NOTCH1) (Notch 1 (NOTCH1))
    Alternative Name
    Notch1 (NOTCH1 Products)
    Synonyms
    notch1 Protein, NOTCH1 Protein, hn1 Protein, tan1 Protein, notch Protein, xotch Protein, xnotch Protein, notch-1 Protein, xnotch1 Protein, TAN1 Protein, hN1 Protein, 9930111A19Rik Protein, Mis6 Protein, N1 Protein, Tan1 Protein, lin-12 Protein, NOTCH Protein, Xotch Protein, notch1-a Protein, notch 1 Protein, fibropellin-1 Protein, Notch homolog 1, translocation-associated (Drosophila) Protein, Notch homolog 1, translocation-associated Protein, notch 1 S homeolog Protein, notch1 Protein, LOC100631526 Protein, NOTCH1 Protein, Notch1 Protein, notch1.S Protein
    Background
    Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.
    Molecular Weight
    ~85kDa (SDS-PAGE)
    UniProt
    Q01705
    Pathways
    Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
You are here:
Support