RBP4 Protein (AA 19-201) (DYKDDDDK Tag)

Catalog No. ABIN1344327

Product Details

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Protein Type: Recombinant

Protein Characteristics: AA 19-201

Origin: Rat

Source: HEK-293 Cells

Purification tag / Conjugate: This RBP4 protein is labelled with DYKDDDDK Tag.

Application: SDS-PAGE (SDS)

Cross-Reactivity: Rat (Rattus)

Characteristics: Rat RBP4 (aa 19-201) is fused at the N-terminus to a FLAG®-tag.

Purity: >90 % (SDS-PAGE)

Sterility: 0.2 μm filtered

Endotoxin Level: <0.1EU/μg purified protein (LAL test, Lonza).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.2.

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.

Expiry Date: 3 months

References

Casillas-Ramírez, Alfany-Fernández, Massip-Salcedo, Juan, Planas, Serafín, Pallàs, Rimola, Rodés, Peralta: "Retinol-binding protein 4 and peroxisome proliferator-activated receptor-? in steatotic liver transplantation." in: The Journal of pharmacology and experimental therapeutics, Vol. 338, Issue 1, pp. 143-53, (2011) (PubMed).

Target Details

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Alternative Name: RBP4 (RBP4 Products)

Synonyms: RDCCAS Protein, RBP Protein, RNBP Protein, rbp4 Protein, MGC54038 Protein, srbp Protein, PRBP Protein, RBPA Protein, Rbp-4 Protein, fb23c12 Protein, rbp Protein, wu:fb23c12 Protein, wu:fb58d04 Protein, wu:fb72b04 Protein, zgc:86911 Protein, retinol binding protein 4 Protein, renin binding protein Protein, retinol binding protein 4 S homeolog Protein, retinol binding protein 4 A, plasma Protein, retinol binding protein 4, plasma Protein, retinol binding protein 4 L homeolog Protein, RBP4 Protein, RENBP Protein, rbp4.S Protein, rbp4 Protein, Rbp4 Protein, RBP4A Protein, rbp4.L Protein

Background: Retinol binding protein 4 (RBP4, RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.

Molecular Weight: ~23kDa (SDS-PAGE)

UniProt: P04916

Pathways: Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response