Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Angiopoietin 2 Protein (ANGPT2) (AA 19-496) (DYKDDDDK Tag)

ANGPT2 Origin: Human, Mouse Host: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS
Catalog No. ABIN1344329
  • Target See all Angiopoietin 2 (ANGPT2) Proteins
    Angiopoietin 2 (ANGPT2)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 19-496
    Origin
    • 21
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Source
    • 17
    • 15
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Angiopoietin 2 protein is labelled with DYKDDDDK Tag.
    Application
    SDS-PAGE (SDS)
    Specificity
    Binds to the human and mouse Tie-2 receptor.
    Cross-Reactivity
    Human, Mouse (Murine)
    Characteristics
    Human angiopoietin-2 (aa 19-496) is fused at the N-terminus to a FLAG®-tag.
    Purity
    >95 % (SDS-PAGE)
    Endotoxin Level
    <0.01EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product ANGPT2 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 100 μL sterile water.
    Concentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS with trehalose and Brij35.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Expiry Date
    6 months
  • Kim, Shin, Kim, Choi, Byun, Jeon, Suh, Kim: "Interaction between Tie receptors modulates angiogenic activity of angiopoietin2 in endothelial progenitor cells." in: Cardiovascular research, Vol. 72, Issue 3, pp. 394-402, (2006) (PubMed).

  • Target
    Angiopoietin 2 (ANGPT2)
    Alternative Name
    Angiopoietin-2 (ANGPT2 Products)
    Synonyms
    AGPT2 Protein, ANG2 Protein, Agpt2 Protein, Ang-2 Protein, Ang2 Protein, ang2 Protein, angpt2 Protein, ANGIOPOIETIN-2 Protein, ANG-2 Protein, ANGPT2 Protein, Angrp Protein, Rnase5b Protein, ANG3 Protein, C11orf2 Protein, C11orf3 Protein, FFR Protein, angiopoietin 2 Protein, angiopoietin 2b Protein, angiogenin, ribonuclease A family, member 2 Protein, VPS51, GARP complex subunit Protein, ANGPT2 Protein, Angpt2 Protein, angpt2b Protein, Ang2 Protein, VPS51 Protein
    Background
    Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.
    Molecular Weight
    ~70kDa (SDS-PAGE)
    UniProt
    O15123
    Pathways
    RTK Signaling
You are here:
Support