TNFSF14 Protein (AA 89-240, Soluble) (DYKDDDDK Tag)
-
- Target See all TNFSF14 Proteins
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- Protein Type
- Recombinant
- Protein Characteristics
- Soluble, AA 89-240
-
Origin
- Human, Mouse
-
Source
- CHO Cells
- Purification tag / Conjugate
- This TNFSF14 protein is labelled with DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Specificity
- Binds to human and mouse LTbetaR and human HVEM and DcR3.
- Cross-Reactivity
- Human, Mouse (Murine)
- Characteristics
- Human LIGHT (aa 89-240) is fused at the N-terminus to a FLAG®-tag.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFSF14 Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Reconstitute with 100 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
-
- Target
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- Abstract
- TNFSF14 Products
- Synonyms
- TNFSF14 Protein, CD258 Protein, HVEML Protein, LIGHT Protein, LTg Protein, TR2 Protein, HVEM-L Protein, Ly113 Protein, TNF superfamily member 14 Protein, tumor necrosis factor (ligand) superfamily, member 14 Protein, TNFSF14 Protein, Tnfsf14 Protein
- Background
- LIGHT (HVEML, CD258) is a cytokine that binds to TNFRSF3/LTBR. It activates NF-kappaB, stimulates the proliferation of T cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
- Molecular Weight
- ~25kDa (SDS-PAGE)
- UniProt
- O43557
- Pathways
- Cancer Immune Checkpoints
-