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CD44 Protein (CD44) (AA 1-699) (GST tag)

CD44 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Catalog No. ABIN1776516
  • Target See all CD44 Proteins
    CD44
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-699
    Origin
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    Wheat germ
    Purification tag / Conjugate
    This CD44 protein is labelled with GST tag.
    Application
    ELISA, Western Blotting (WB), Affinity Purification (AP), Antibody Array (AA)
    Purpose
    CD44 (Human) Recombinant Protein (P01)
    Sequence
    MDKFWWHAAW GLCLVPLSLA QIDLNITCRF AGVFHVEKNG RYSISRTEAA DLCKAFNSTL PTMAQMEKAL SIGFETCRYG FIEGHVVIPR IHPNSICAAN NTGVYILTSN TSQYDTYCFN ASAPPEEDCT SVTDLPNAFD GPITITIVNR DGTRYVQKGE YRTNPEDIYP SNPTDDDVSS GSSSERSSTS GGYIFYTFST VHPIPDEDSP WITDSTDRIP ATSTSSNTIS AGWEPNEENE DERDRHLSFS GSGIDDDEDF ISSTISTTPR AFDHTKQNQD WTQWNPSHSN PEVLLQTTTR MTDVDRNGTT AYEGNWNPEA HPPLIHHEHH EEEETPHSTS TIQATPSSTT EETATQKEQW FGNRWHEGYR QTPREDSHST TGTAAASAHT SHPMQGRTTP SPEDSSWTDF FNPISHPMGR GHQAGRRMDM DSSHSTTLQP TANPNTGLVE DLDRTGPLSM TTQQSNSQSF STSHEGLEED KDHPTTSTLT SSNRNDVTGG RRDPNHSEGS TTLLEGYTSH YPHTKESRTF IPVTSAKTGS FGVTAVTVGD SNSNVNRSLS GDQDTFHPSG GSHTTHGSES DGHSHGSQEG GANTTSGPIR TPQIPEWLII LASLLALALI LAVCIAVNSR RRCGQKKKLV INSGNGAVED RKPSGLNGEA SKSQEMVHLV NKESSETPDQ FMTADETRNL QNVDMKIGV
    Characteristics
    Human CD44 full-length ORF ( AAH04372, 1 a.a. - 699 a.a.) recombinant protein with GST-tag at N-terminal.
    Purification
    in vitro wheat germ expression system
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Preparation method: in vitro, wheat germ expression system
    Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

    Restrictions
    For Research Use only
  • Buffer
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -80 °C
    Storage Comment
    Best use within three months from the date of receipt of this protein.
  • Gebhard, Jain, Nair, Emmons, Argilagos, Koomen, McLaughlin, Hazlehurst: "MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma." in: Molecular cancer therapeutics, Vol. 12, Issue 11, pp. 2446-58, (2013) (PubMed).

    Ababneh, Alshaer, Allozi, Mahafzah, El-Khateeb, Hillaireau, Noiray, Fattal, Ismail: "In vitro selection of modified RNA aptamers against CD44 cancer stem cell marker." in: Nucleic acid therapeutics, Vol. 23, Issue 6, pp. 401-7, (2013) (PubMed).

  • Target
    CD44
    Alternative Name
    CD44 (CD44 Products)
    Background
    Full Gene Name: CD44 Molecule (Indian blood group)
    Synonyms: CDW44,CSPG8,ECMR-III,HCELL,IN,LHR,MC56,MDU2,MDU3,MGC10468,MIC4,MUTCH-I,Pgp1
    Gene ID
    960
    Pathways
    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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