F12 Protein (AA 20-368) (His tag)

Catalog No. ABIN1459540

Product Details

Target: F12 (Coagulation Factor XII (F12))

Protein Type: Recombinant

Protein Characteristics: AA 20-368

Origin: Cow

Source: Yeast

Purification tag / Conjugate: This F12 protein is labelled with His tag.

Application: ELISA

Sequence: T PPWKGPKKHK LTDSEHTVVL TVTGEPCHFP FQYHRQLHHK CIHRGRPGPR PWCATTPNFE KDQRWAYCLE PKKVKDHCSK HNPCQKGGTC VNMPDGPRCI CADHFTGKHC QKEKCFEPQF FRFFHENEIW HRLEPAGVVK CQCKGPNAQC KPLASQVCRT NPCLNGGSCL QAEGHRLCRC APSFAGRLCD VDLKASCYDD RDRGLSYRGM AGTTLSGAPC QSWASEATYW NVTAEQVLNW GLGDHAFCRA STPPRGYRNP DNDTRPLCFI WKGDRLSWNY CRLAPCQAAA GHEHFPLPSP SALQKPESTT QTPLPSLTSG WCSPTPLASG GPGGCGQRLR KWLSSLNR

Specificity: Bos taurus (Bovine)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: F12 (Coagulation Factor XII (F12))

Abstract: F12 Products

Synonyms: HAE3 Protein, HAEX Protein, HAF Protein, FXII Protein, coagulation factor XII Protein, coagulation factor XII (Hageman factor) Protein, F12 Protein

Background: Recommended name: Coagulation factor XII.
EC= 3.4.21.38.
Alternative name(s): Hageman factor.
Short name= HAF Cleaved into the following 2 chains: 1.
Coagulation factor XIIa heavy chain 2.
Coagulation factor XIIa light chain

UniProt: P98140

Pathways: Complement System