PCSK2 Protein (AA 109-637) (His tag)

Catalog No. ABIN1474565

Product Details

Target: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Protein Type: Recombinant

Protein Characteristics: AA 109-637

Origin: Rat

Source: Yeast

Purification tag / Conjugate: This PCSK2 protein is labelled with His tag.

Application: ELISA

Sequence: GY RDINEIDINM NDPLFTKQWY LFNTGQADGT PGLDLNVAEA WELGYTGKGV TIGIMDDGID YLHPDLAYNY NSDASYDFSS NDPYPYPRYT DDWFNSHGTR CAGEVSAAAS NNICGVGVAY NSKVAGIRML DQPFMTDIIE ASSISHMPQL IDIYSASWGP TDNGKTVDGP RELTLQAMAD GVNKGRGGKG SIYVWASGDG GSYDDCNCDG YASSMWTISI NSAINDGRTA LYDESCSSTL ASTFSNGRKR NPEAGVATTD LYGNCTLRHS GTSAAAPEAA GVFALALEAN VDLTWRDMQH LTVLTSKRNQ LHDEVHQWRR NGVGLEFNHL FGYGVLDAGA MVKMAKDWKT VPERFHCVGG SVQNPEKIPP TGKLVLTLQT NACEGKENFV RYLEHVQAVI TVNATRRGDL NINMTSPMGT KSILLSRRPR DDDSKVGFDK WPFMTTHTWG EDARGTWTLE LGFVGSAPQK GLLKEWTLML HGTQSAPYID QVVRDYQSKL AMSKKQELEE ELDEAVERSL QSILRKN

Specificity: Rattus norvegicus (Rat)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Alternative Name: Neuroendocrine convertase 2 (Pcsk2) (PCSK2 Products)

Synonyms: NEC 2 Protein, NEC-2 Protein, NEC2 Protein, PC2 Protein, SPC2 Protein, PCSK2 Protein, 6330411F23Rik Protein, AI839700 Protein, Nec-2 Protein, Nec2 Protein, Phpp-2 Protein, pc2 Protein, nec2 Protein, spc2 Protein, pcsk2 Protein, pcsk2-A Protein, proprotein convertase subtilisin/kexin type 2 Protein, proprotein convertase subtilisin/kexin type 2 L homeolog Protein, PCSK2 Protein, pcsk2 Protein, Pcsk2 Protein, pcsk2.L Protein

Background: Recommended name: Neuroendocrine convertase 2.
Short name= N.
EC 2.
EC= 3.4.21.94.
Alternative name(s): KEX2-like endoprotease 2 Prohormone convertase 2 Proprotein convertase 2.
Short name= PC2

UniProt: P28841

Pathways: Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity