IL-6 Protein (AA 30-208, full length) (His tag)

Catalog No. ABIN7479112

Product Details

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Protein Type: Recombinant

Protein Characteristics: AA 30-208, full length

Origin: Sheep

Source: Yeast

Purification tag / Conjugate: This IL-6 protein is labelled with His tag.

Application: ELISA

Sequence: GPLGEDFKND TTPSRLLLTT PEKTEALIKH IVDKISAIRK EICEKNDECE NSKETLAENK LKLPKMEEKD GCFQSGFNQA ICLIKTTAGL LEYQIYLDFL QNEFEGNQET VMELQSSIRT LIQILKEKIA GLITTPATHT DMLEKMQSSN EWVKNAKVII ILRSLENFLQ FSLRAIRMK

Specificity: Ovis aries (Sheep)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Alternative Name: Interleukin-6 (IL6) (IL6 Products)

Background: Recommended name: Interleukin-6.
Short name= IL-6

Molecular Weight: 22.4 kD

UniProt: P29455

Pathways: TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome