DKC1 Protein (AA 1-474) (His tag)

Catalog No. ABIN1510156

Product Details

Target: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Protein Type: Recombinant

Protein Characteristics: AA 1-474

Origin: Schizosaccharomyces pombe

Source: Yeast

Purification tag / Conjugate: This DKC1 protein is labelled with His tag.

Application: ELISA

Sequence: MTDTHPGVDF MIKPEATSAS KIDTAEWPLL LKNFDKLLVR TGHYTPIPCG NNPLKRPIAE YVSSGVINLD KPANPSSHEV VAWVKKILRV EKTGHSGTLD PKVTGCLIIC NDRATRLVKS QQSAGKEYVC VLRLHDSVEG ERNVASAIET LTGALFQRPP LISAVKRQLR IRSIYESKLI EFDNERNLAV FWASCEAGTY MRTLCVHLGL LLGVGGHMQE LRRVRSGCLS ENDDIVTMHD VLDAQWIYDN TRDESYLRRV IRPLESLLVG YKRIVVKDSA VNAICYGAKL MIPGLLRYEA GIEVNEEIVL ITTKGEAIAV GIAQMSTVEL STCDHGVVAK VKRCIMERDV YPRRWGLGPQ SMKKKTLKKE GKLDKYGRPN ENTPADWSKS YIDYSDPNAE VAKPAPVVAP AAPTVEAEVN GVEDSKKRKS VESSEKDEDE AAKKEEKRRK KEAKKEKKEK KEKKEKKEKK KKSE

Specificity: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Alternative Name: H/ACA ribonucleoprotein complex subunit 4 (cbf5) (DKC1 Products)

Synonyms: CBF5 Protein, DKC Protein, DKCX Protein, NAP57 Protein, NOLA4 Protein, XAP101 Protein, dyskerin Protein, fv62a07 Protein, wu:fa28f10 Protein, wu:fc87a02 Protein, wu:fi24a05 Protein, wu:fv62a07 Protein, zgc:110395 Protein, DKC1 Protein, cbf5 Protein, dkc Protein, nap57 Protein, nola4 Protein, xap101 Protein, BC068171 Protein, Nap57 Protein, AtCBF5 Protein, AtNAP57 Protein, homologue of NAP57 Protein, dyskerin pseudouridine synthase 1 Protein, microRNA 664b Protein, dyskeratosis congenita 1, dyskerin Protein, dyskeratosis congenita 1, dyskerin L homeolog Protein, homologue of NAP57 Protein, DKC1 Protein, MIR664B Protein, dkc1 Protein, dkc1.L Protein, Dkc1 Protein, NAP57 Protein

Background: Recommended name: H/ACA ribonucleoprotein complex subunit 4.
EC= 5.4.99.-.
Alternative name(s): Centromere-binding factor 5 homolog

UniProt: O14007

Pathways: Telomere Maintenance