PSMA7 Protein (AA 5-232, partial) (GST tag)
-
- Target See all PSMA7 Proteins
- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 5-232, partial
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PSMA7 protein is labelled with GST tag.
- Application
- ELISA
- Sequence
- RAITVFSPDG HLFQVEYAQE AVKKGSTAVG VRGRDIVVLG VEKKSVAKLQ DERTVRKICA LDDNVCMAFA GLTADARIVI NRARVECQSH RLTVEDPVTV EYITRYIASL KQRYTQSNGR RPFGISALIV GFDFDGTPRL YQTDPSGTYH AWKANAIGRG AKSVREFLEK NYTDEAIETD DLTIKLVIKA LLEVVQSGGK NIELAVMRRD QSLKILNPEE IEKYVAEI
- Characteristics
- Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
- Purity
- 95 %
- Top Product
- Discover our top product PSMA7 Protein
-
-
- Comment
-
The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Concentration
- 0.2-2 mg/mL
- Buffer
- Tris-based buffer, 50 % glycerol
- Handling Advice
- Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
-
- Target
- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
- Alternative Name
- Proteasome subunit alpha type-7 protein (PSMA7 Products)
- Synonyms
- C6 Protein, HSPC Protein, RC6-1 Protein, XAPC7 Protein, C6-I Protein, DDBDRAFT_0185059 Protein, DDBDRAFT_0217080 Protein, DDB_0185059 Protein, DDB_0217080 Protein, hspc Protein, rc6-1 Protein, xapc7 Protein, psma7 Protein, psma4-B Protein, proteasome subunit alpha 7 Protein, proteasome (prosome, macropain) subunit, alpha type 7 Protein, 20S proteasome subunit alpha-7 Protein, proteasome subunit alpha 7 S homeolog Protein, proteasome subunit alpha 7 L homeolog Protein, PSMA7 Protein, Psma7 Protein, psmA7 Protein, psma7 Protein, psma7.S Protein, psma7.L Protein
- Background
- The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
- Molecular Weight
- 52.8 kD
- UniProt
- O14818
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
-