SHC1 Protein (AA 1-465) (His tag)

Catalog No. ABIN1625324

Product Details

Target: SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))

Protein Type: Recombinant

Protein Characteristics: AA 1-465

Origin: Xenopus laevis

Source: Yeast

Purification tag / Conjugate: This SHC1 protein is labelled with His tag.

Application: ELISA

Sequence: MNKLSCGRKS RVEGGQLAGD EWTRHGSFVN KPTRGWLHPD DKVMGPGVPY LVRYMGCVEV LQSMRALDFN TRTQVTREAI SLVCDAVPGA KGAMRRRKTC GRSLNSILGK SNLKFAGMPI TLTVSTSSLN LMASDCKQII ANHHMQSISF ASGGDPDTAE YVAYVAKDPV NQRACHILEC PEGLAQDVIS TIGQAFELRF KQYLKNPPKL VTPHDRMAGF DGSAWDEEEE ELPDHAYYND FPGKEPPIGG VVDMRLRDGA APAVLRQSPN HMGATLPVGQ VSGAEQDSRK MQPTLQGRER FPVPCSRPPN RPDLFDDPSY VNVQNLEKSR QPLRAANGQR DIFDMKPFDD ALPSAQAIVS MEDQLKREPW YQGKMSRKEA ERLLKVNGDF LVRESTTTPG QYVLTGLQCG QPKHLLLVDP EGVVRTKDHR FESVSHLISY HMDNHLPIIS AGSELCLQQP VERRQ

Specificity: Xenopus laevis (African clawed frog)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))

Alternative Name: SHC-transforming protein 1 (shc1) (SHC1 Products)

Background: Recommended name: SHC-transforming protein 1.
Alternative name(s): Src homology 2 domain-containing-transforming protein C1.
Short name= SH2 domain protein C1 p60Shc

UniProt: Q8AY68

Pathways: RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, ER-Nucleus Signaling, Signaling Events mediated by VEGFR1 and VEGFR2